Evidence map›Paper›PMID 31533343›Full record

ArticleCancers2019

João Lobo, Sandra P Nunes, Ad J M Gillis, Daniela Barros-Silva, Vera Miranda-Gonçalves, Annette van den Berg, Mariana Cantante, Rita Guimarães, Rui Henrique, Carmen Jerónimo and 1 more

Open access · goldAbstract read
In one paragraph

Article in Cancers, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 24 papers.

0numbers the graph read from it
0cells of the map it votes in
24citing papers in PubMed
4.4field-weighted citation impact, top 5% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

24 citing papers in PubMed, 32 citations in OpenAlex.

  1. Review
  2. Article
  3. Review
  4. Article
  5. Review
  6. Article
  7. Review
  8. Epigenetic Factors and ncRNAs in Testicular Cancer.International journal of molecular sciences · 2023
    Review
  9. Review
  10. Article
  11. Review
  12. Article
  13. Review
  14. Review
  15. Review
  16. Article
  17. Review
  18. Biological Function of Long Non-coding RNA (LncRNA) Xist.Frontiers in cell and developmental biology · 2021
    Review
  19. Epigenetics of Male Infertility: The Role of DNA Methylation.Frontiers in cell and developmental biology · 2021
    Review
  20. Abnormal X chromosome inactivation and tumor development.Cellular and molecular life sciences : CMLS · 2020
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors at 3 institutions in 2 countries.

João LoboPrincess Máxima Center for Pediatric Oncology, Heidelberglaan 25, 3584 CS Utrecht, The Netherlands. joaomachadolobo@gmail.com.
Sandra P NunesCancer Biology and Epigenetics Group, Research Center of Portuguese Oncology Institute of Porto (GEBC CI-IPOP) and Porto Comprehensive Cancer Center (P.CCC), R. Dr. António Bernardino de Almeida, 4200-072 Porto, Portugal. sandra22nunes@gmail.com.
Ad J M GillisPrincess Máxima Center for Pediatric Oncology, Heidelberglaan 25, 3584 CS Utrecht, The Netherlands. a.j.m.gillis@prinsesmaximacentrum.nl.
Daniela Barros-SilvaCancer Biology and Epigenetics Group, Research Center of Portuguese Oncology Institute of Porto (GEBC CI-IPOP) and Porto Comprehensive Cancer Center (P.CCC), R. Dr. António Bernardino de Almeida, 4200-072 Porto, Portugal. daniela.barros.silva94@gmail.com.
Vera Miranda-GonçalvesCancer Biology and Epigenetics Group, Research Center of Portuguese Oncology Institute of Porto (GEBC CI-IPOP) and Porto Comprehensive Cancer Center (P.CCC), R. Dr. António Bernardino de Almeida, 4200-072 Porto, Portugal. verammgoncalves@hotmail.com.
Annette van den BergPrincess Máxima Center for Pediatric Oncology, Heidelberglaan 25, 3584 CS Utrecht, The Netherlands. ritaguimaraes.apct@gmail.com.
Mariana CantanteDepartment of Pathology, Portuguese Oncology Institute of Porto (IPOP), R. Dr. António Bernardino de Almeida, 4200-072 Porto, Portugal. marianacantantecf@gmail.com.
Rita GuimarãesDepartment of Pathology, Portuguese Oncology Institute of Porto (IPOP), R. Dr. António Bernardino de Almeida, 4200-072 Porto, Portugal. ritaguimaraes.apct@gmail.com.
Rui HenriqueDepartment of Pathology, Portuguese Oncology Institute of Porto (IPOP), R. Dr. António Bernardino de Almeida, 4200-072 Porto, Portugal. henrique@ipoporto.min-saude.pt.
Carmen JerónimoCancer Biology and Epigenetics Group, Research Center of Portuguese Oncology Institute of Porto (GEBC CI-IPOP) and Porto Comprehensive Cancer Center (P.CCC), R. Dr. António Bernardino de Almeida, 4200-072 Porto, Portugal. carmenjeronimo@ipoporto.min-saude.pt.
Leendert H J LooijengaPrincess Máxima Center for Pediatric Oncology, Heidelberglaan 25, 3584 CS Utrecht, The Netherlands. l.looijenga@prinsesmaximacentrum.nl.
Instituto Português de Oncologia Francisco Gentil · PTPrincess Máxima Center · NLUniversidade do Porto · PT

Funding

FCT - Fundação para a Ciência e Tecnologia POCI-01-0145-FEDER-29043FCT - Fundação para a Ciência e Tecnologia SFRH/BD/132751/2017
6 · The paper itself

Abstract

backgroundThe event of X chromosome inactivation induced by

methodsTwo independent cohorts were included, comprising a total of 413 TGCT samples, four (T)GCT cell lines, and 86 testicular parenchyma samples. The relative amount of methylated and demethylated

resultsSeminomas showed a lower amount of methylated

conclusionsThe X chromosome inactivation event and demethylated

Indexed as

methylationmolecular biomarkersspermatogenesistesticular germ cell tumorsXIST promoter

Identifiers

PMID31533343
PMCPMC6769809
OpenAlexW2974334552

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.