Evidence map›Paper›PMID 31533244›Full record

ReviewViruses2019

An Update on African Swine Fever Virology.

Axel Karger, Daniel Pérez-Núñez, Jesús Urquiza, Patricia Hinojar, Covadonga Alonso, Ferdinando B Freitas, Yolanda Revilla, Marie-Frédérique Le Potier, Maria Montoya

Open access · goldAbstract readReview
In one paragraph

Review in Viruses, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 101 papers.

0numbers the graph read from it
0cells of the map it votes in
101citing papers in PubMed
17.2field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

101 citing papers in PubMed, 145 citations in OpenAlex.

  1. Article
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  5. Review
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  8. Implications for safety:Frontiers in microbiology · 2026
    Article
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  10. Review
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41 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 6 institutions in 4 countries.

Axel KargerInstitute of Molecular Virology and Cell Biology, Friedrich Loeffler Institut, Federal Research Institute for Animal Health, Südufer 10, 17493 Greifswald-Insel Riems, Germany. axel.karger@fli.de.ORCID 0000-0002-0054-7394
Daniel Pérez-NúñezVirology Department, Centro Biología Molecular Severo Ochoa, CSIC-UAM, 28049 Madrid, Spain. daniel_perez@cbm.csic.es.
Jesús UrquizaINIA, Instituto Nacional de Investigación y Tecnología Agraria y Alimentaria, 28040 Madrid, Spain. chuslucena12@gmail.com.ORCID 0000-0002-7870-4580
Patricia HinojarINIA, Instituto Nacional de Investigación y Tecnología Agraria y Alimentaria, 28040 Madrid, Spain.
Covadonga AlonsoINIA, Instituto Nacional de Investigación y Tecnología Agraria y Alimentaria, 28040 Madrid, Spain. calonso@inia.es.ORCID 0000-0002-0862-6177
Ferdinando B FreitasCentre for Interdisciplinary Research in Animal Health (CIISA), Faculty of Veterinary Medicine, University of Lisbon, 1649-004 Lisboa, Portugal. FerdinandoFreitas@fmv.ulisboa.pt.ORCID 0000-0002-1218-5052
Yolanda RevillaVirology Department, Centro Biología Molecular Severo Ochoa, CSIC-UAM, 28049 Madrid, Spain. yrevilla@cbm.csic.es.
Marie-Frédérique Le PotierANSES, Laboratoire de Ploufragan/Plouzané/Niort, Unité Virologie Immunologie Porcines, Anses, 22440 Ploufragan, France. marie-frederique.lepotier@anses.fr.ORCID 0000-0003-3929-9129
Maria MontoyaCentro de Investigaciones Biológicas (CIB-CSIC), Ramiro de Maeztu 9, 28040 Madrid, Spain. maria.montoya@cib.csic.es.ORCID 0000-0002-5703-7360
Instituto Nacional de Investigación y Tecnología Agraria y Alimentaria · ESCentro de Biología Molecular Severo Ochoa · ESAgence Nationale de Sécurité Sanitaire de l’Alimentation, de l’Environnement et du Travail · FRCentro de Investigaciones Biológicas Margarita Salas · ESFriedrich-Loeffler-Institut · DEUniversity of Lisbon · PT

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Animal diseases constitute a continuing threat to animal health, food safety, national economy, and the environment. Among those, African swine fever (ASF) is one of the most devastating viruses affecting pigs and wild suids due to the lack of vaccine or effective treatment. ASF is endemic in countries in sub-Saharan Africa, but since its introduction to the Caucasus region in 2007, a highly virulent strain of ASF virus (ASFV) has continued to circulate and spread into Eastern Europe and Russia, and most recently into Western Europe, China, and various countries of Southeast Asia. Given the importance of this disease, this review will highlight recent discoveries in basic virology with special focus on proteomic analysis, replication cycle, and some recent data on genes involved in cycle progression and viral-host interactions, such as I215L (E2 ubiquitin-conjugating enzyme), EP402R (CD2v), A104R (histone-like protein), QP509L, and Q706L (RNA helicases) or P1192R (Topoisomerase II). Taking into consideration the large DNA genome of ASFV and its complex interactions with the host, more studies and new approaches are to be taken to understand the basic virus-host interaction for ASFV. Proteomic studies are just paving the way for future research.

Indexed as

Host-Pathogen InteractionsProteomicsAfrican Swine FeverAfrican Swine Fever VirusAmino Acid SubstitutionAnimalsRNA HelicasesSwineViral ProteinsRNA HelicasesViral ProteinsAfrican swine fever virusproteomicsvirologyvirus–host interaction

Identifiers

PMID31533244
PMCPMC6784044
OpenAlexW2973949370

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.