Evidence map›Paper›PMID 31533011›Full record

ArticleJournal of neurophysiology2019

Nerve excitability differences in slow and fast motor axons of the rat: more than just

James M Bell, Chad Lorenz, Kelvin E Jones

Open access · bronzeAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Journal of neurophysiology, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
0.3field-weighted citation impact, top 38% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed, 3 citations in OpenAlex.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 1 institution in 1 country.

James M BellNeuroscience and Mental Health Institute, University of Alberta, Edmonton, Alberta, Canada.
Chad LorenzFaculty of Kinesiology, Sport and Recreation, University of Alberta, Edmonton, Alberta, Canada.
Kelvin E JonesNeuroscience and Mental Health Institute, University of Alberta, Edmonton, Alberta, Canada.ORCID 0000-0003-4764-7031
University of Alberta · CA

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The objective was to determine biophysical differences between fast and slow motor axons using threshold tracking and demonstrate confounds related to anesthetic. Nerve excitability of motor axons innervating the slow-twitch soleus (SOL) and fast-twitch tibialis anterior (TA) muscles was tested. The experiments were conducted with pentobarbital sodium (SP) anesthetic and compared with previous results that used ketamine-xylazine (KX). Nerve excitability indices measured with SP show definitive differences between TA and SOL motor axons that extend beyond previous reports. Nerve excitability indices sensitive to changes in

Indexed as

Action PotentialsAnimalsAxonsFemaleKetamineMotor NeuronsMuscle Fibers, Fast-TwitchMuscle Fibers, Slow-TwitchPeripheral NervesRatsRats, Sprague-DawleySodium ChannelsXylazineKetamineSodium ChannelsXylazineanesthetic effectaxon excitabilityHCN currention channelssciatic nerve

Identifiers

PMID31533011
PMCPMC6843099
OpenAlexW2974249061

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.