Evidence map›Paper›PMID 31533007›Full record

ArticleJournal of neurophysiology2019

Case studies in neuroscience: a novel amino acid duplication in the NH

Madeline Angus, Colin H Peters, Damon Poburko, Elise Brimble, Emily M Spelbrink, Peter C Ruben

Open access · greenAbstract readCase Reports
PubMed Full text at PMC Publisher
In one paragraph

Article in Journal of neurophysiology, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
0.1field-weighted citation impact, top 57% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 1 citations in OpenAlex.

  1. Persistent sodium currents inBrain communications · 2021
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 3 institutions in 2 countries.

Madeline AngusDepartment of Biomedical Physiology, Simon Fraser University, Burnaby, British Columbia, Canada.
Colin H PetersDepartment of Physiology and Biophysics, University of Colorado Anschutz Medical Campus, Aurora, Colorado.
Damon PoburkoDepartment of Biomedical Physiology, Simon Fraser University, Burnaby, British Columbia, Canada.
Elise BrimbleDepartment of Neurology and Neurological Sciences, Stanford Medicine, Palo Alto, California.
Emily M SpelbrinkDepartment of Neurology and Neurological Sciences, Stanford Medicine, Palo Alto, California.
Peter C RubenDepartment of Biomedical Physiology, Simon Fraser University, Burnaby, British Columbia, Canada.
Simon Fraser University · CAStanford Medicine · USUniversity of Colorado Anschutz Medical Campus · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Dravet syndrome is a severe form of childhood epilepsy characterized by frequent temperature-sensitive seizures and delays in cognitive development. In the majority (80%) of cases, Dravet syndrome is caused by mutations in the SCN1A gene, encoding the voltage-gated sodium channel Na

Indexed as

Epilepsies, MyoclonicFemaleHumansImmunohistochemistryInfantNAV1.1 Voltage-Gated Sodium ChannelNeurosciencesPatch-Clamp TechniquesNAV1.1 Voltage-Gated Sodium ChannelSCN1A protein, humanDravet syndromeloss of functionNaV1.1SCN1A

Identifiers

PMID31533007
PMCPMC6879963
OpenAlexW2973924143

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.