ArticlePLoS neglected tropical diseases2019
The genetic structure of Aedes aegypti populations is driven by boat traffic in the Peruvian Amazon.
Article in PLoS neglected tropical diseases, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. An erratum has been issued. Cited by 17 papers.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
17 citing papers in PubMed, 28 citations in OpenAlex.
- Fine-Scale Landscape Genomics Show Asymmetric Patterns of Gene Flow for the Invasive MosquitoEcology and evolution · 2026Article
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- Dengue vaccine acceptability in Peru: A mixed-methods study in two dengue-endemic Peruvian cities.PLoS neglected tropical diseases · 2026Article
- Presence of Dengue Virus NS1 antigen and IgM and IgG antibodies in asymptomatic individuals in Ecuadorian Amazonia - a descriptive repeated cross-sectional community-based survey.New microbes and new infections · 2026Article
- Highway paving increased dengue transmission in the Peruvian Amazon.medRxiv : the preprint server for health sciences · 2025Article
- Changing dynamics of Aedes aegypti invasion and vector-borne disease risk for rural communities in the Peruvian Amazon.PLoS neglected tropical diseases · 2025Article
- Effect of chikungunya, Mayaro and Una virus coinfection on vector competence ofOne health (Amsterdam, Netherlands) · 2025Article
- Genetic structure and kdr mutations in Aedes aegypti populations along a road crossing the Amazon Forest in Amapá State, Brazil.Scientific reports · 2023Article
- Article
- Correction: The genetic structure of Aedes aegypti populations is driven by boat traffic in the Peruvian Amazon.PLoS neglected tropical diseases · 2022Article
- Fine-scale genetic structure andFrontiers in genetics · 2022Article
- Mosquito Control Priorities in Florida-Survey Results from Florida Mosquito Control Districts.Pathogens (Basel, Switzerland) · 2021Article
- The influence of roads on the fine-scale population genetic structure of the dengue vector Aedes aegypti (Linnaeus).PLoS neglected tropical diseases · 2021Article
- Population structure and ancestry prediction of Aedes aegypti (Diptera: Culicidae) supports a single African origin of Colombian populations.Memorias do Instituto Oswaldo Cruz · 2021Article
- Gene Drive Dynamics in Natural Populations: The Importance of Density Dependence, Space, and Sex.Annual review of ecology, evolution, and systematics · 2020Article
- Article
- Fine-scale population genetic structure of dengue mosquito vector, Aedes aegypti, in Metropolitan Manila, Philippines.PLoS neglected tropical diseases · 2020Article
Corrections and comments
- Erratum issued
Authors and funding
12 authors at 3 institutions in 2 countries.
Funding
Abstract
In the Americas, as in much of the rest of the world, the dengue virus vector Aedes aegypti is found in close association with human habitations, often leading to high population densities of mosquitoes in urban settings. In the Peruvian Amazon, this vector has been expanding to rural communities over the last 10-15 years, but to date, the population genetic structure of Ae. aegypti in this region has not been characterized. To investigate the relationship between Ae. aegypti gene flow and human transportation networks, we characterized mosquito population structure using a panel of 8 microsatellite markers and linked results to various potential mechanisms for long-distance dispersal. Adult and immature Ae. aegypti (>20 individuals per site) were collected from Iquitos city and from six neighboring riverine communities, i.e., Nauta, Indiana, Mazan, Barrio Florida, Tamshiaco, and Aucayo. FST statistics indicate significant, but low to moderate differentiation for the majority of study site pairs. Population structure of Ae. aegypti is not correlated with the geographic distance between towns, suggesting that human transportation networks provide a reasonable explanation for the high levels of population mixing. Our results indicate that Ae. aegypti gene flow among sub-populations is greatest between locations with heavy boat traffic, such as Iquitos-Tamshiaco and Iquitos-Indiana-Mazan, and lowest between locations with little or no boat/road traffic between them such as Barrio Florida-Iquitos. Bayesian clustering analysis showed ancestral admixture among three genetic clusters; no single cluster was exclusive to any site. Our results are consistent with the hypothesis that human transportation networks, particularly riverways, are responsible for the geographic spread of Ae. aegypti in the Peruvian Amazon. Our findings are applicable to other regions of the world characterized by networks of urban islands connected by fluvial transport routes.
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