Evidence map›Paper›PMID 31532725›Full record

SynthesisJournal of clinical oncology : official journal of the American Society of Clinical Oncology2019

Effect of Psychological Intervention on Fear of Cancer Recurrence: A Systematic Review and Meta-Analysis.

Nina M Tauber, Mia S O'Toole, Andreas Dinkel, Jacqueline Galica, Gerry Humphris, Sophie Lebel, Christine Maheu, Gozde Ozakinci, Judith Prins, Louise Sharpe and 4 more

2 registry-linked trialsAbstract readMeta-AnalysisSystematic Review
PubMed Full text at PMC Publisher
In one paragraph

Synthesis in Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to 2 registered trials, which are not on this map. Cited by 201 papers, 22 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
201citing papers in PubMed, 22 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT04287218 nacompletednot on this mapstarted 2023, after this paper: background citation

A Randomized Controlled Trial Comparing the Efficacy of Therapist Guided Internet-delivered Cognitive Therapy (TG-iConquerFear) With Augmented Treatment as Usual in Reducing Fear of Cancer Recurrence in Danish Colorectal Cancer Survivors

TypeinterventionalSponsorVejle HospitalRan2023 to 2026Enrolled95ConditionsFear of Cancer Recurrence, Colorectal Cancer, Anxiety, Health AnxietyArmsTG-iConquerFear, aTAU
NCT06614647 narecruitingnot on this mapstarted 2024, after this paper: background citation

RESPONSE: Colorectal Cancer Survivors' Follow-up Care - Now Digital and Need-based: A National Interventional Effectiveness Trial for Stage I and II Patients

TypeinterventionalSponsorUniversity of AarhusRan2024 to 2030Enrolled400ConditionsColorectal Cancer, Quality of Life, SurvivorshipArmsRecurrence monitoring with circulating tumor DNA (ctDNA) as a high risk biomarker, Monitoring for late adverse effects with electronic patient reported outcome measures (ePROMs), Systematic treatment of organ-specific late effects and/or biopsychosocial late effects, Digital care-guide for long-term follow-up after cancer treatment
3 · Its place in the literature

Who cites it

201 citing papers in PubMed, 22 syntheses or guidelines pooled it.

  1. How prevalent is fear of cancer recurrence beyond 5 years: a systematic review of validated assessments across tumour types.Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer · 2026
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  2. Guideline
  3. Patient-reported emotional responses and coping mechanisms in cancer recurrence: a systematic review of qualitative evidence.Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer · 2025
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  7. The effectiveness of solution-focused therapy in cancer-related symptom management: a systematic review.Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer · 2024
    Pooled it
  8. Ecosystem Barriers and Facilitators Linked to the Fear of Cancer Recurrence: An Umbrella Review.International journal of environmental research and public health · 2024
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  13. Guideline
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  15. Mind-body practices for cancer-related symptoms management: an overview of systematic reviews including one hundred twenty-nine meta-analyses.Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer · 2022
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141 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

14 authors.

Nina M TauberAarhus University, Aarhus, Denmark.
Mia S O'TooleAarhus University, Aarhus, Denmark.
Andreas DinkelInternational Psycho-Oncology Society Fear of Cancer Recurrence Special Interest Group, Toronto, Ontario, Canada.
Jacqueline GalicaInternational Psycho-Oncology Society Fear of Cancer Recurrence Special Interest Group, Toronto, Ontario, Canada.
Gerry HumphrisInternational Psycho-Oncology Society Fear of Cancer Recurrence Special Interest Group, Toronto, Ontario, Canada.
Sophie LebelInternational Psycho-Oncology Society Fear of Cancer Recurrence Special Interest Group, Toronto, Ontario, Canada.
Christine MaheuInternational Psycho-Oncology Society Fear of Cancer Recurrence Special Interest Group, Toronto, Ontario, Canada.
Gozde OzakinciInternational Psycho-Oncology Society Fear of Cancer Recurrence Special Interest Group, Toronto, Ontario, Canada.
Judith PrinsInternational Psycho-Oncology Society Fear of Cancer Recurrence Special Interest Group, Toronto, Ontario, Canada.
Louise SharpeInternational Psycho-Oncology Society Fear of Cancer Recurrence Special Interest Group, Toronto, Ontario, Canada.
Allan Ben SmithInternational Psycho-Oncology Society Fear of Cancer Recurrence Special Interest Group, Toronto, Ontario, Canada.
Belinda ThewesInternational Psycho-Oncology Society Fear of Cancer Recurrence Special Interest Group, Toronto, Ontario, Canada.
Sébastien SimardInternational Psycho-Oncology Society Fear of Cancer Recurrence Special Interest Group, Toronto, Ontario, Canada.
Robert ZachariaeAarhus University, Aarhus, Denmark.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

purposeFear of cancer recurrence (FCR) is a significantly distressing problem that affects a substantial number of patients with and survivors of cancer; however, the overall efficacy of available psychological interventions on FCR remains unknown. We therefore evaluated this in the present systematic review and meta-analysis.

methodsWe searched key electronic databases to identify trials that evaluated the effect of psychological interventions on FCR among patients with and survivors of cancer. Controlled trials were subjected to meta-analysis, and the moderating influence of study characteristics on the effect were examined. Overall quality of evidence was evaluated using the GRADE system. Open trials were narratively reviewed to explore ongoing developments in the field (PROSPERO registration no.: CRD42017076514).

resultsA total of 23 controlled trials (21 randomized controlled trials) and nine open trials were included. Small effects (Hedges's

conclusionPsychological interventions for FCR revealed a small but robust effect at postintervention, which was largely maintained at follow-up. Larger postintervention effects were found for contemporary CBTs that were focused on processes of cognition-for example, worry, rumination, and attentional bias-rather than the content, and aimed to change the way in which the individual relates to his or her inner experiences. Future trials could investigate how to further optimize and tailor interventions to individual patients' FCR presentation.

Indexed as

Cognitive Behavioral TherapyFearAdaptation, PsychologicalAdultAgedCancer SurvivorsFemaleHumansMaleMiddle AgedNeoplasm Recurrence, LocalNeoplasmsPhobic DisordersRandomized Controlled Trials as TopicRisk FactorsTreatment Outcome

Identifiers

PMID31532725
PMCPMC6823887

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.