ArticleChemistry (Weinheim an der Bergstrasse, Germany)2019
Copper-Catalyzed Enantio- and Diastereoselective Addition of Silicon Nucleophiles to 3,3-Disubstituted Cyclopropenes.
Article in Chemistry (Weinheim an der Bergstrasse, Germany), 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.
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Who cites it
9 citing papers in PubMed.
- Recent advances and perspectives in synthetic applications of silylboronates as silyl radical precursors.Chemical science · 2025Review
- Metal-catalysed C-C bond formation at cyclopropanes.Nature reviews. Chemistry · 2023Review
- Copper-Catalyzed Highly Enantioselective Addition of a Silicon Nucleophile to 3-Substituted 2H-Azirines Using an Si-B Reagent.Angewandte Chemie (International ed. in English) · 2023Article
- Copper-Catalyzed Enantioselective Hydrosilylation of gem-Difluorocyclopropenes Leading to a Stereochemical Study of the Silylated gem-Difluorocyclopropanes.Chemistry (Weinheim an der Bergstrasse, Germany) · 2022Article
- Silylative aromatization ofRSC advances · 2021Article
- Beyond Carbon: Enantioselective and Enantiospecific Reactions with Catalytically Generated Boryl- and Silylcopper Intermediates.ACS central science · 2020Review
- Cobalt-Catalyzed Diastereoselective and Enantioselective Hydrosilylation of Achiral Cyclopropenes.Organic letters · 2020Article
- Recent advances in Cu-catalyzed C(spBeilstein journal of organic chemistry · 2020Review
- Copper-Catalyzed Enantio- and Diastereoselective Addition of Silicon Nucleophiles to 3,3-Disubstituted Cyclopropenes.Chemistry (Weinheim an der Bergstrasse, Germany) · 2019Article
Corrections and comments
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Authors and funding
2 authors.
Funding
Abstract
A highly stereocontrolled syn-addition of silicon nucleophiles across cyclopropenes with two different geminal substituents at C3 is reported. Diastereomeric ratios are excellent throughout (d.r.≥98:2) and enantiomeric excesses usually higher than 90 %, even reaching 99 %. This copper-catalyzed C-Si bond formation closes the gap of the direct synthesis of α-chiral cyclopropylsilanes.
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Registered trials
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