Evidence map›Paper›PMID 31531850›Full record

Observational studyAnaesthesia2019

The relationship between obstructive sleep apnoea and postoperative delirium and pain: an observational study of a surgical cohort.

P K Strutz, V Kronzer, W Tzeng, B Arrington, S L McKinnon, A Ben Abdallah, S Haroutounian, M S Avidan

Open access · greenAbstract readObservational Study
In one paragraph

Observational study in Anaesthesia, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers, 4 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
16citing papers in PubMed, 4 pooled it
1.4field-weighted citation impact, top 18% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

16 citing papers in PubMed, 4 syntheses or guidelines pooled it, 27 citations in OpenAlex.

  1. Systematic review of the association between sleep apnea and postoperative complications after ENT surgery.European archives of oto-rhino-laryngology : official journal of the European Federation of Oto-Rhino-Laryngological Societies (EUFOS) : affiliated with the German Society for Oto-Rhino-Laryngology - Head and Neck Surgery · 2025
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4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

8 authors at 3 institutions in 1 country.

P K StrutzDepartment of Anesthesiology, Washington University School of Medicine in St. Louis, MO, USA.
V KronzerDepartment of Medicine, Mayo Clinic, Rochester, MN, USA.
W TzengDepartment of Anesthesiology, Washington University School of Medicine in St. Louis, MO, USA.
B ArringtonMeharry Medical College, Nashville, TN, USA.
S L McKinnonDepartment of Anesthesiology, Washington University School of Medicine in St. Louis, MO, USA.
A Ben AbdallahDepartment of Anesthesiology, Washington University School of Medicine in St. Louis, MO, USA.
S HaroutounianDepartment of Anesthesiology, Washington University School of Medicine in St. Louis, MO, USA.
M S AvidanDepartment of Anesthesiology, Washington University School of Medicine in St. Louis, MO, USA.
Washington University in St. Louis · USMayo Clinic in Arizona · USMeharry Medical College · US

Funding

Washington University Institute of Clinical and Translational Sciences (TL1)TL1TR002344 · NCATS · WASHINGTON UNIVERSITY · PI Jay F. Piccirillo · 2017 to 2026
$8.5M
Supplement to Network for Investigation of Delirium across the U.S (NIDUS)R24AG054259 · NIA · HEBREW REHABILITATION CENTER FOR AGED · PI INOUYE, SHARON K. · 2016 to 2020
$4.3M
SHORT-TERM TRAINING STUDENTS IN HEALTH PROFESSIONAL SCHOT35HL007815 · NHLBI · WASHINGTON UNIVERSITY · PI CHUNG, KOONG-NAH · 1995 to 2020
$2.8M
ELECTROENCEPHALOGRAPH GUIDANCE OF ANESTHESIA TO ALLEVIATE GERIATRIC SYNDROMES (ENGAGES)UH3AG050312 · NIA · WASHINGTON UNIVERSITY · PI AVIDAN, MICHAEL SIMON · 2015 to 2018
$2.4M
Electroencephalograph Guidance of Anesthesia to Alleviate Geriatric Syndromes (ENUH2AG050312 · NIA · WASHINGTON UNIVERSITY · PI AVIDAN, MICHAEL SIMON · 2014 to 2014
$483k
CPAP ADHERENCE AND POSTOPERATIVE DELIRIUM IN PATIENTS WITH OSAR21HL123666 · NHLBI · WASHINGTON UNIVERSITY · PI AVIDAN, MICHAEL SIMON · 2016 to 2017
$229k
2017-Washington University School of Medicine Meharry Summer Research ProgramNational Institutes of Health NIDUS R24AG054259National Institutes of Health (NIH) 5R21HL123666National Institutes of Health (NIH) 5T35HL007815National Institutes of Health (NIH) TL1TR002344NCATS NIH HHS TL1 TR002344NHLBI NIH HHS R21 HL123666NHLBI NIH HHS T35 HL007815NIA NIH HHS 5 UH3 AG050312NIA NIH HHS R24 AG054259NIA NIH HHS UH2 AG050312NIA NIH HHS UH2AG050312NIA NIH HHS UH3 AG050312Washington University
6 · The paper itself

Abstract

Patients with obstructive sleep apnoea are at increased risk of adverse postoperative outcomes, such as cardiac and respiratory complications. It has been hypothesised that obstructive sleep apnoea also increases the risk for postoperative delirium and acute postoperative pain. We conducted a retrospective, observational study investigating the relationship of obstructive sleep apnoea with postoperative delirium and acute postoperative pain severity. Patients were classified as being at high risk for obstructive sleep apnoea if they had been diagnosed with this condition, or if they were positive for more than four factors using the 'STOP-BANG' screening tool. Adjusted logistic regression was used to investigate the association between obstructive sleep apnoea and postoperative delirium, and multivariable linear regression to study the relationship between obstructive sleep apnoea and postoperative pain severity. The incidence of postoperative delirium was 307 in 1441 patients (21.3%; 95%CI 19.2-23.5%). In unadjusted analysis, high risk for obstructive sleep apnoea was associated with delirium, with an odds ratio (95%CI) of 1.77 (1.22-2.57; p = 0.003). After adjustment for pre-specified variables, the association was not statistically significant with odds ratio 1.34 (0.80-2.23; p = 0.27). The mean (SD) maximum pain (resting or provoked) reported for the entire cohort was 63.8 (27.9) mm on a 0-100 mm visual analogue scale. High risk for obstructive sleep apnoea was not associated with postoperative pain severity (β-coefficient 2.82; 95%CI, -2.34-7.97; p = 0.28). These findings suggest that obstructive sleep apnoea is unlikely to be a strong risk factor for postoperative delirium or acute postoperative pain severity.

Indexed as

AdultAgedAged, 80 and overCohort StudiesEmergence DeliriumFemaleHumansIncidenceMaleMass ScreeningMiddle AgedPain MeasurementPostoperative PainRetrospective StudiesRisk FactorsSleep Apnea, Obstructivedeliriumpain, postoperativesleep apnoea, obstructive

Identifiers

PMID31531850
PMCPMC6829039
OpenAlexW2974738805

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.