SynthesisQuality of life research : an international journal of quality of life aspects of treatment, care and rehabilitation2019
A comprehensive catalogue of EQ-5D scores in chronic disease: results of a systematic review.
Synthesis in Quality of life research : an international journal of quality of life aspects of treatment, care and rehabilitation, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 53 papers, 2 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
53 citing papers in PubMed, 2 syntheses or guidelines pooled it, 85 citations in OpenAlex.
- A systematic review of health state utility values for older people with acute myeloid leukaemia.Quality of life research : an international journal of quality of life aspects of treatment, care and rehabilitation · 2024Pooled it
- Quality appraisal for systematic literature reviews of health state utility values: a descriptive analysis.BMC medical research methodology · 2022Pooled it
- Sacubitril/valsartan and quality of life assessed using the EuroQol Five-dimension Three-level questionnaire level sum score (EQ-5D-3L-LSS) in patients with HFrEF and HFmrEF/HFpEF.European heart journal. Cardiovascular pharmacotherapy · 2025Trial
- Comparison of the effect of aerobic and resistance training on fatigue, quality of life and biochemical factors in hemodialysis patients.Scientific reports · 2025Trial
- Depressive symptoms decrease health-related quality of life of patients with coronary artery disease and diabetes: a 12-month follow up study in primary care.Scandinavian journal of primary health care · 2023Trial
- Improving quality of life in older dialysis patients: the case for broader functional assessment.Clinical kidney journal · 2026Article
- Real-world impact of mepolizumab on symptom control and health utility in severe chronic rhinosinusitis with nasal polyps: the RINOSUR 2.0 multicenter cohort study.European archives of oto-rhino-laryngology : official journal of the European Federation of Oto-Rhino-Laryngological Societies (EUFOS) : affiliated with the German Society for Oto-Rhino-Laryngology - Head and Neck Surgery · 2026Article
- Patient- and provider-level determinants of self-assessed health and well-being among adults with chronic conditions in Slovenian primary care.Health and quality of life outcomes · 2026Article
- The Meaning of Chronic Disease Management in the Patient's Environment: A Critical Ethnographic Study.Healthcare (Basel, Switzerland) · 2026Article
- Health-related quality of life in patients with alcohol use disorder: comparing instruments and mapping from clinical measures to preference-based measures.The European journal of health economics : HEPAC : health economics in prevention and care · 2026Article
- Health-related quality of life among adults with chronic diseases: a linked, retrospective cohort study using the EQ-5D-5L in Queensland, Australia.Quality of life research : an international journal of quality of life aspects of treatment, care and rehabilitation · 2026Article
- Cost-effectiveness of atrial fibrillation screening programmes across European nations.European heart journal. Quality of care & clinical outcomes · 2026Article
- Deep inspiration breath-hold for breast cancer radiotherapy: a modelling study of targeted versus non-targeted strategy for clinical and operational optimisation.The Lancet regional health. Europe · 2026Article
- Assessing the quality of life in patients with complex chronic conditions: Cronimad study.BMC geriatrics · 2025Article
- Health-related quality of life in the UK Biobank Experience of Pain follow-up study: a comparison with general population norms.American journal of epidemiology · 2025Article
- Quality of Life in Adult Patients With SAPHO Syndrome and Chronic Nonbacterial Osteomyelitis, and Comparison to Chronic Rheumatic and Inflammatory Diseases.The Journal of rheumatology · 2025Article
- The impact of sociodemographic, health status and health behavior factors on depression and quality of life in older adults.BMC public health · 2025Article
- Association of throat sensation severity with quality of life in patients with chronic cough.Journal of thoracic disease · 2025Article
- Disutility associated with social isolation and loneliness in Germany: results of a population survey using the EQ-5D-5L instrument.Health and quality of life outcomes · 2024Article
- Exploring social determinants of health and their impacts on self-reported quality of life in long COVID-19 patients.Scientific reports · 2024Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
6 authors at 2 institutions in 1 country.
Funding
Abstract
purposeChronic diseases are associated with impaired health-related quality of life (HRQoL) outcomes. Comparison of HRQoL outcomes between different diseases and with the general population is of major importance to health economists, epidemiologists, clinicians, and policy makers. The aim of this systematic literature review was to develop a catalogue with EQ-5D scores in chronic non-communicable diseases, and to compare these scores with reference values from the general population.
methodsMEDLINE, Embase, and Web of Science were systematically searched independently by two reviewers. Studies were included if they reported mean EQ-5D index values for the adult population and if these scores were compared with the general population. The QualSyst tool for quantitative research was used for quality appraisal.
resultsTwo hundred and seven articles met the inclusion criteria. An extensive catalogue summarizes the EQ-5D scores in a wide variety of chronic diseases. Mean EQ-5D index values ranged between - 0.20 and 1. Lower EQ-5D scores are reported in chronic diseases compared to the general population, specifically in neurological disorders. Most of the diseases demonstrate a substantial disutility, although a minority of diseases have equal or even higher index scores than the general population.
conclusionA comprehensive, international catalogue has been developed to provide EQ-5D index scores for diverse chronic diseases compared with reference values based on the available literature. The catalogue gives a clear overview of the existing EQ-5D scores and can be rapidly accessed by researchers worldwide for different applications such as health economic evaluations, decision making, resource allocation, and other policy objectives. Future studies should focus on unexamined diseases and specific patient groups to expand the evidence base on HRQoL in chronic diseases.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.