ArticleDigestive diseases and sciences2020
Predicting 30-Day Hospital Readmission Risk in a National Cohort of Patients with Cirrhosis.
Article in Digestive diseases and sciences, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 19 papers.
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Who cites it
19 citing papers in PubMed, 27 citations in OpenAlex.
- A Doubly Robust Approach to Evaluating the Impact of Hospital Length of Stay on Post-Fracture Recovery in Older Adults With Cognitive Impairment.Statistics in medicine · 2026Article
- Investigation of the impact of social, behavioral, and pre-existing clinical risk factors on preeclampsia.BMC pregnancy and childbirth · 2026Article
- Longitudinal Inpatient Trajectories After Splenic Artery Embolization in Cirrhosis: Real-World Evidence from Kazakhstan.Journal of clinical medicine · 2026Article
- Article
- Readmission Rate, Predictors, Outcomes, and Burden of Readmission of Hepatorenal Syndrome in the United States: A Nationwide Analysis.JGH open : an open access journal of gastroenterology and hepatology · 2024Article
- Assessment of the 2021 AASLD Practice Guidance for Albumin Infusion in Elective Therapeutic Paracentesis: A Regression Discontinuity Design.The American journal of gastroenterology · 2024Article
- Measuring Medication Use, Obstacles, and Knowledge in Individuals With Cirrhosis.Clinical gastroenterology and hepatology : the official clinical practice journal of the American Gastroenterological Association · 2023Article
- Confusion assessment method accurately screens for hepatic encephalopathy and predicts short-term mortality in hospitalized patients with cirrhosis.Metabolic brain disease · 2023Article
- A risk score to predict 30-day hospital readmission rate in cirrhotic patients with spontaneous bacterial peritonitis.European journal of medical research · 2023Article
- The Need to Prioritize Model-Updating Processes in Clinical Artificial Intelligence (AI) Models: Protocol for a Scoping Review.JMIR research protocols · 2023Article
- Hepatic Encephalopathy-Related Hospitalizations in Cirrhosis: Transition of Care and Closing the Revolving Door.Digestive diseases and sciences · 2022Review
- Patient-Reported Outcome Measures Modestly Enhance Prediction of Readmission in Patients with Cirrhosis.Clinical gastroenterology and hepatology : the official clinical practice journal of the American Gastroenterological Association · 2022Article
- Artificial Intelligence and the Future of Gastroenterology and Hepatology.Gastro hep advances · 2022Review
- Prediction of Hospital Readmission from Longitudinal Mobile Data Streams.Sensors (Basel, Switzerland) · 2021Article
- Reducing readmissions in patients with cirrhosis: the time to act is now.Annals of translational medicine · 2021Article
- The 30-days hospital readmission risk in diabetic patients: predictive modeling with machine learning classifiers.BMC medical informatics and decision making · 2021Article
- Risk Stratification Score to Predict Readmission of Patients With Acute Decompensated Cirrhosis Within 90 Days.Frontiers in medicine · 2021Article
- Skeletal muscle loss phenotype in cirrhosis: A nationwide analysis of hospitalized patients.Clinical nutrition (Edinburgh, Scotland) · 2020Article
- Development of a national Department of Veterans Affairs mortality risk prediction model among patients with cirrhosis.BMJ open gastroenterology · 2019Article
Corrections and comments
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Authors and funding
7 authors at 4 institutions in 2 countries.
Funding
Abstract
backgroundEarly hospital readmission for patients with cirrhosis continues to challenge the healthcare system. Risk stratification may help tailor resources, but existing models were designed using small, single-institution cohorts or had modest performance.
aimsWe leveraged a large clinical database from the Department of Veterans Affairs (VA) to design a readmission risk model for patients hospitalized with cirrhosis. Additionally, we analyzed potentially modifiable or unexplored readmission risk factors.
methodsA national VA retrospective cohort of patients with a history of cirrhosis hospitalized for any reason from January 1, 2006, to November 30, 2013, was developed from 123 centers. Using 174 candidate variables within demographics, laboratory results, vital signs, medications, diagnoses and procedures, and healthcare utilization, we built a 47-variable penalized logistic regression model with the outcome of all-cause 30-day readmission. We excluded patients who left against medical advice, transferred to a non-VA facility, or if the hospital length of stay was greater than 30 days. We evaluated calibration and discrimination across variable volume and compared the performance to recalibrated preexisting risk models for readmission.
resultsWe analyzed 67,749 patients and 179,298 index hospitalizations. The 30-day readmission rate was 23%. Ascites was the most common cirrhosis-related cause of index hospitalization and readmission. The AUC of the model was 0.670 compared to existing models (0.649, 0.566, 0.577). The Brier score of 0.165 showed good calibration.
conclusionOur model achieved better discrimination and calibration compared to existing models, even after local recalibration. Assessment of calibration by variable parsimony revealed performance improvements for increasing variable inclusion well beyond those detectable for discrimination.
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.