Evidence map›Paper›PMID 31531798›Full record

Trial reportCancer causes & control : CCC2019

Post-operative colorectal cancer surveillance: preference for optical colonoscopy over computerized tomographic colonography.

David S Weinberg, Jeremy Mitnick, Eileen Keenan, Tianyu Li, Eric A Ross

Registry-linked trialOpen access · greenAbstract readClinical TrialComparative StudyMulticenter Study
In one paragraph

Trial report in Cancer causes & control : CCC, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT02143115 (Comparative Effectiveness of Virtual and Optical Colonoscopy for Colorectal), which is not on this map. Cited by 3 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed, 1 pooled it
0.3field-weighted citation impact, top 37% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT02143115 completednot on this map

Comparative Effectiveness of Virtual and Optical Colonoscopy for Colorectal (CRC) Surveillance

TypeobservationalSponsorFox Chase Cancer CenterRan2011 to 2016Enrolled244ConditionsColorectal CancerArmsOptical colonoscopy, CT-Colonography
3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 1 synthesis or guideline pooled it, 5 citations in OpenAlex.

  1. Guideline
  2. CT colonography: revisited after 30 years.Insights into imaging · 2025
    Article
  3. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 1 institution in 1 country.

David S WeinbergFox Chase Cancer Center, Philadelphia, PA, USA. david.weinberg@fccc.edu.
Jeremy MitnickFox Chase Cancer Center, Philadelphia, PA, USA.
Eileen KeenanFox Chase Cancer Center, Philadelphia, PA, USA.
Tianyu LiFox Chase Cancer Center, Philadelphia, PA, USA.
Eric A RossFox Chase Cancer Center, Philadelphia, PA, USA.
Fox Chase Cancer Center · US

Funding

WORD PROCESSING CENTER--COREP30CA006927 · NCI · RESEARCH INST OF FOX CHASE CAN CTR · PI Dietmar J Kappes · 1985 to 2026
$138.8M
Comparative Effectiveness of Virtual and Optical Colonoscopy for CRC SurveillanceR01CA155347 · NCI · RESEARCH INST OF FOX CHASE CAN CTR · PI WEINBERG, DAVID S · 2011 to 2015
$3.3M
NCI NIH HHS P30 CA006927NCI NIH HHS R01 CA155347NIH HHS NIH RO1 CA155347
6 · The paper itself

Abstract

purposePost-operative surveillance strategies for colorectal cancer (CRC) include periodic optical colonoscopy (OC) and abdominal-pelvic CT scan. Adherence with these recommendations is limited. For CRC screening, CT colonography (CTC) identifies larger adenomas and cancers nearly as well as OC. Most screening studies demonstrate that patients prefer CTC. However, CTC has never been compared to OC in the post-operative surveillance setting.

methodsWe hypothesized that CTC might represent an attractive substitute for the standard OC/CT scan combination. Here, 223 patients underwent CTC followed by same day OC 1 year after curative CRC resection.

resultsOf the 144/223 (64.6%) participants with a preference, 65.9% (95/144) preferred OC. This preference was more pronounced in women and in patients with polyps detected. No additional patient level factors significantly altered this primary result.

conclusionsIn contrast to CRC screening, this first study in CRC post-operative surveillance patients demonstrates a preference for OC. Assuming patient preference is an important determinant, introduction of CTC as a method to increase patient adherence with CRC surveillance is unlikely to be effective.

trial registrationClinical Trials.gov registration number: NCT02143115.

Indexed as

Colonography, Computed TomographicColonoscopyPatient PreferenceAdultAgedColorectal NeoplasmsEarly Detection of CancerFemaleHumansMaleMiddle AgedPostoperative PeriodColonoscopyColorectal cancerCT colonographyPost-operative surveillance

Identifiers

PMID31531798
PMCPMC7534185
OpenAlexW2974012012

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.