Evidence map›Paper›PMID 31531627›Full record

ArticleRevista do Instituto de Medicina Tropical de Sao Paulo2019

Hospital-acquired intestinal toxemia botulism in a newly diagnosed adult colon cancer patient.

Lucas José Sá da Fonseca, Diogo Couto de Carvalho, Helena Providelli de Moraes, Izabela Dayany França Feitosa, Gil Pereira Neto, Rodrigo Vasconcellos Vilela, Breno Franco Silveira Fernandes, Rodrigo Santiago Gomez, Vandack Nobre

Open access · diamondAbstract readCase Reports
PubMed Full text at PMC Publisher
In one paragraph

Article in Revista do Instituto de Medicina Tropical de Sao Paulo, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
0.5field-weighted citation impact, top 33% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 3 citations in OpenAlex.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 1 institution in 1 country.

Lucas José Sá da FonsecaUniversidade Federal de Alagoas, Hospital Universitário Professor Alberto Antunes, Unidade de Reumatologia, Maceió, Alagoas, Brazil.ORCID http://orcid.org/0000-0002-8850-841X
Diogo Couto de CarvalhoUniversidade Federal de Minas Gerais, Hospital das Clínicas, Departamento de Medicina Interna, Belo Horizonte, Minas Gerais, Brazil.
Helena Providelli de MoraesUniversidade Federal de Minas Gerais, Hospital das Clínicas, Departamento de Neurologia, Belo Horizonte, Minas Gerais, Brazil.
Izabela Dayany França FeitosaUniversidade Federal de Minas Gerais, Hospital das Clínicas, Departamento de Neurologia, Belo Horizonte, Minas Gerais, Brazil.
Gil Pereira NetoUniversidade Federal de Minas Gerais, Hospital das Clínicas, Departamento de Neurologia, Belo Horizonte, Minas Gerais, Brazil.
Rodrigo Vasconcellos VilelaUniversidade Federal de Minas Gerais, Hospital das Clínicas, Departamento de Neurologia, Belo Horizonte, Minas Gerais, Brazil.
Breno Franco Silveira FernandesUniversidade Federal de Minas Gerais, Hospital das Clínicas, Departamento de Neurologia, Belo Horizonte, Minas Gerais, Brazil.
Rodrigo Santiago GomezUniversidade Federal de Minas Gerais, Hospital das Clínicas, Departamento de Neurologia, Belo Horizonte, Minas Gerais, Brazil.
Vandack NobreUniversidade Federal de Minas Gerais, Hospital das Clínicas, Departamento de Medicina Interna, Unidade de Terapia Intensiva, Belo Horizonte, Minas Gerais, Brazil.
Universidade Federal de Minas Gerais · BR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

This manuscript reports a case of intestinal toxemia botulism in an adult with recently diagnosed metastatic colon cancer in whom botulism symptoms began 23 days after hospital admission. Representing the rarest form of botulism presentation in clinical practice, this infectious disease may have developed due to a cluster of predisposing factors that favored Clostridium botulinum colonization and the endogenous production of neurotoxins, among which are previous use of broad-spectrum antibiotics and colon changes related to the development of the neoplasia. This case highlights the importance of considering intestinal toxemia botulism in the differential diagnosis of a patient presenting with symmetrical descending flaccid paralysis, since immediate treatment with botulinum antitoxin may improve clinical outcomes.

Indexed as

BotulismColonic NeoplasmsCross InfectionFatal OutcomeFecesHumansIntestinal DiseasesMaleMiddle AgedToxemia

Identifiers

PMID31531627
PMCPMC6746195
OpenAlexW2972862038

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.