Evidence map›Paper›PMID 31531571›Full record

ReviewClinics (Sao Paulo, Brazil)2019

Review of the missed opportunities for the prevention of vertical transmission of HIV in Brazil.

Mariana Fernandes Guimarães, Kathryn Lynn Lovero, Juliana Gregório de Avelar, Laís Lopes Pires, Giovanna Rodrigues Teixeira de Oliveira, Estela Magalhães Cosme, Camila de Morais Salviato, Thais Raquelly Dourado de Oliveira, Natália Beatriz Cabrera, Claudete Aparecida Araújo Cardoso

Open access · goldAbstract readReview
In one paragraph

Review in Clinics (Sao Paulo, Brazil), 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed
1.6field-weighted citation impact, top 17% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed, 30 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
  4. HIV infection during pregnancy in the state of Rio de Janeiro, Brazil, 2021-2023.Revista brasileira de epidemiologia = Brazilian journal of epidemiology · 2025
    Article
  5. Antiretroviral medications for pediatric use in the context of the Unified Health System: are there therapeutic gaps in Brazil?Revista paulista de pediatria : orgao oficial da Sociedade de Pediatria de Sao Paulo · 2025
    Article
  6. Article
  7. Evaluating elimination of mother-to-child transmission of HIV in Suriname: a mixed method study.Revista panamericana de salud publica = Pan American journal of public health · 2023
    Article
  8. Article
  9. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 2 institutions in 2 countries.

Mariana Fernandes GuimarãesDepartamento Materno-Infantil, Faculdade de Medicina, Universidade Federal Fluminense, Niteroi, RJ, BR.ORCID 0000-0002-9863-599X
Kathryn Lynn LoveroInfectious Diseases, Berkeley School of Public Health, University of California, California, US.ORCID 0000-0001-6067-8663
Juliana Gregório de AvelarDepartamento Materno-Infantil, Faculdade de Medicina, Universidade Federal Fluminense, Niteroi, RJ, BR.ORCID 0000-0002-4870-2568
Laís Lopes PiresDepartamento Materno-Infantil, Faculdade de Medicina, Universidade Federal Fluminense, Niteroi, RJ, BR.ORCID 0000-0003-4750-0558
Giovanna Rodrigues Teixeira de OliveiraDepartamento Materno-Infantil, Faculdade de Medicina, Universidade Federal Fluminense, Niteroi, RJ, BR.ORCID 0000-0001-8069-2155
Estela Magalhães CosmeDepartamento Materno-Infantil, Faculdade de Medicina, Universidade Federal Fluminense, Niteroi, RJ, BR.ORCID 0000-0003-0157-763X
Camila de Morais SalviatoDepartamento Materno-Infantil, Faculdade de Medicina, Universidade Federal Fluminense, Niteroi, RJ, BR.ORCID 0000-0001-7507-6382
Thais Raquelly Dourado de OliveiraDepartamento Materno-Infantil, Faculdade de Medicina, Universidade Federal Fluminense, Niteroi, RJ, BR.ORCID 0000-0001-5642-5751
Natália Beatriz CabreraDepartamento Materno-Infantil, Faculdade de Medicina, Universidade Federal Fluminense, Niteroi, RJ, BR.ORCID 0000-0003-1736-4006
Claudete Aparecida Araújo CardosoDepartamento Materno-Infantil, Faculdade de Medicina, Universidade Federal Fluminense, Niteroi, RJ, BR.ORCID 0000-0002-7638-6814
Universidade Federal Fluminense · BRBerkeley Public Health Division · US

Funding

Research Mentoring and Building Capacity of underrepresented Minority Research Scientists in India.D43TW010540 · FIC · YALE UNIVERSITY · PI MICHELE BARRY, Eva Harris · 2017 to 2026
$15.5M
Global Health Fellows and Scholars Research TrainingR25TW009338 · FIC · UNIVERSITY OF CALIFORNIA BERKELEY · PI BARRY, MICHELE, KO, ALBERT ICKSANG · 2012 to 2016
$5.2M
FIC NIH HHS D43 TW010540FIC NIH HHS R25 TW009338
6 · The paper itself

Abstract

objectiveThe present literature review aims to highlight gaps in the treatment of preventative mother-to-child HIV transmission and the risk factors in Brazil.

methodsAmong the 425 articles identified in SciELO and PubMed searches, 59 articles published between 1994 and 2016 were selected for reading and data extraction, and 33 articles were included in the present review.

resultsThe rates of vertical HIV transmission described in the studies varied widely, from 1.8% to 27.8%, with a significant reduction over the years. However, recent rates were also found to be variable in different regions of Brazil, and despite the significant reduction in mother-to-child transmission, many gaps remain in prevention services. A failure to attend prenatal care is the main factor associated with the increased risk of vertical transmission of HIV, hindering early maternal diagnosis and the completion of preventative measures during the prenatal period and, often, the peripartum and postnatal periods. A small number of studies discussed the sociodemographic factors, including a low level of education for pregnant women and the inadequacies of health services, such as difficulties scheduling appointments and undertrained staff, associated with vertical transmission. As such, the current challenge is to better define the sociodemographic and infrastructural factors that increase the risk of mother-to-child transmission of HIV to provide the necessary investments to promote an earlier inclusion of these populations in prevention services.

conclusionsThis review may serve as a guide for future programs to focus efforts on the prevention of vertical HIV transmission.

Indexed as

Anti-HIV AgentsBrazilDrug Therapy, CombinationFemaleHIV InfectionsHumansInfectious Disease Transmission, VerticalPregnancyPregnancy Complications, InfectiousPrenatal CareRisk FactorsZidovudineAnti-HIV AgentsZidovudine

Identifiers

PMID31531571
PMCPMC6735274
OpenAlexW2973407272

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.