Evidence map›Paper›PMID 31531570›Full record

ArticleClinics (Sao Paulo, Brazil)2019

Evaluation of the discrepancy between clinical diagnostic hypotheses and anatomopathological diagnoses resulting from autopsies.

Talita Zerbini, Julio M Singer, Vilma Leyton

Abstract read
In one paragraph

Article in Clinics (Sao Paulo, Brazil), 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

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2 · The registry

The trial behind it

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3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

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4 · The record

Corrections and comments

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5 · Who and what money

Authors and funding

3 authors.

Talita ZerbiniDepartamento de Medicina Legal, Etica Medica e Medicina Social e do Trabalho, Faculdade de Medicina FMUSP, Universidade de Sao Paulo, Sao Paulo, SP, BR.ORCID 0000-0001-8814-9210
Julio M SingerInstituto de Matematica e Estatistica, Universidade de Sao Paulo, Sao Paulo, SP, BR.ORCID 0000-0001-6515-9643
Vilma LeytonDepartamento de Medicina Legal, Etica Medica e Medicina Social e do Trabalho, Faculdade de Medicina FMUSP, Universidade de Sao Paulo, Sao Paulo, SP, BR.ORCID 0000-0002-5101-1290

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectivesAn objective of clinical autopsies is to determine the final cause of death and the pathological changes that may have triggered it. Despite advances in Medicine, the level of discrepancy between clinical and autopsy diagnoses remains significant. The aim of this study was to compare the data obtained from autopsies carried out at the São Bernardo do Campo/SP Death Verification Section with clinical diagnostic hypotheses proposed during medical care.

methodThis was a retrospective study involving the comparison of necroscopic reports issued by the São Bernardo do Campo/São Paulo Death Verification Section in 2014 and 2015 and the Cadaver Referral Guides completed by attending physicians prior to the necroscopic examination.

resultsA total of 465 cases were analyzed. In general, discrepancies between the clinical diagnostic hypothesis and the autopsy diagnosis occurred in 28% of the cases. A logistic regression model, with diagnostic discrepancy as a response variable and sex, age, duration of care, type of institution providing medical care and organ system as explanatory variables, was fit to the data; the results indicated that all explanatory variables with the exception of organ system are not significant (p>0.132).

conclusionsDiscrepancies between clinical diagnostic hypotheses and autopsy diagnoses continue to occur, despite new developments in complementary examinations and therapies. The odds of a discrepancy when patients present with diseases of the cardiac system are greater than those when there are problems in the vascular, endocrine and neurological systems.

Indexed as

AdolescentAdultAgedAge FactorsAutopsyCause of DeathChildChild, PreschoolDiagnostic ErrorsDuration of TherapyFemaleHumansInfantLogistic ModelsMaleMiddle Aged

Identifiers

PMID31531570
PMCPMC6735273

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