Evidence map›Paper›PMID 31531537›Full record

ArticleActa cirurgica brasileira2019

Intermittent vibrations accelerate fracture healing in sheep.

Degong Mu, Jing Yu, Junhao Lin, Chen Li, Baohui Hao, Feng Gu, Chao Liu, Lei Tan, Dong Zhu, Xizheng Zhang

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Acta cirurgica brasileira, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
0.4field-weighted citation impact, top 38% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 2 citations in OpenAlex.

  1. Article
  2. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 3 institutions in 2 countries.

Degong MuBachelor, Operating Theatre 3, the First Hospital of Jilin University, Changchun, China. Conception and design of the study, analysis and interpretation of data, manuscript writing.ORCID http://orcid.org/0000-0003-3377-411X
Jing YuMaster, Operating Theatre 1, the First Hospital of Jilin University, Changchun, China. Manuscript writing.ORCID http://orcid.org/0000-0002-4692-612X
Junhao LinMaster, College of Mechanical Science and Engineering, Jilin University, Changchun, China. Statistics analysis.ORCID http://orcid.org/0000-0001-6860-9187
Chen LiMaster, Department of Orthopedic Traumatology, the First Hospital of Jilin University, Changchun, China. Technical procedures.ORCID http://orcid.org/0000-0002-0224-1380
Baohui HaoMaster, Department of Orthopedic Traumatology, the First Hospital of Jilin University, Changchun, China. Technical procedures, interpretation of data, critical revision.ORCID http://orcid.org/0000-0002-2994-3323
Feng GuMaster, Department of Orthopedic Traumatology, the First Hospital of Jilin University, Changchun, China. Technical procedures, interpretation of data.ORCID http://orcid.org/0000-0001-6111-5467
Chao LiuMaster, Department of Orthopedic Traumatology, the First Hospital of Jilin University, Changchun, China. Statistics analysis.ORCID http://orcid.org/0000-0003-0572-1125
Lei TanPhD, Department of Orthopedic Traumatology, the First Hospital of Jilin University, Changchun, China. Analysis and interpretation of data, critical revision.ORCID http://orcid.org/0000-0001-7886-5811
Dong ZhuPhD, Department of Orthopedic Traumatology, the First Hospital of Jilin University, Changchun, China. Conception and design of the study, analysis and interpretation of data, critical revision.ORCID http://orcid.org/0000-0002-6046-0872
Xizheng ZhangPhD, Institute of Medical Equipment, Academy of Military Medical Sciences, Tianjin, China. Critical revision.ORCID http://orcid.org/0000-0002-2387-9017
Jilin University · CNAcademy of Military Medical Sciences · CNJilin University of Finance and Economics · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

purposeTo investigate the effect of intermittent vibration at different intervals on bone fracture healing and optimize the vibration interval.

methodsNinety sheep were randomized to receive no treatment (the control group), incision only (the sham control group), internal fixation with or without metatarsal fracture (the internal fixation group), and continuous vibration in addition to internal fixation of metatarsal fracture, or intermittent vibration at 1, 2, 3, 5, 7 and 17-day interval in addition to internal fixation of metatarsal fracture (the vibration group). Vibration was done at frequency F=35 Hz, acceleration a=0.25g, 15 min each time 2 weeks after bone fracture. Bone healing was evaluated by micro-CT scan, bone microstructure and mechanical compression of finite element simulation.

resultsIntermittent vibration at 7-day interval significantly improved bone fracture healing grade. However, no significant changes on microstructure parameters and mechanical properties were observed among sheep receiving vibration at different intervals.

conclusionsClinical healing effects should be the top concern. Quantitative analyses of bone microstructure and of finite element mechanics on the process of fracture healing need to be further investigated.

Indexed as

Fracture HealingFractures, BoneMetatarsal BonesVibrationAnimalsFinite Element AnalysisFracture Fixation, InternalRandom AllocationSheepX-Ray Microtomography

Identifiers

PMID31531537
PMCPMC6746562
OpenAlexW2972789315

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.