ArticleEnvironmental epidemiology (Philadelphia, Pa.)2018
Multiple mediators approach to study environmental chemicals as determinants of health disparities.
Article in Environmental epidemiology (Philadelphia, Pa.), 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers.
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Who cites it
14 citing papers in PubMed.
- Evaluating the mediating role of gestational phthalate and replacement biomarkers in the associations between race/ethnicity and birthweight.Environmental epidemiology (Philadelphia, Pa.) · 2026Article
- A pipeline for enabling path-specific causal fairness in observational health data.Proceedings of the ... Conference on Fairness, Accountability, and Transparency · 2026Article
- Public drinking water contaminant estimates for birth cohorts in the Environmental Influences on Child Health Outcomes (ECHO) Cohort.Journal of exposure science & environmental epidemiology · 2026Article
- Testing the Development of a Diet-Based Bisphenol a Score to Facilitate Studies on Child Neurodevelopment: A Pilot Project.International journal of environmental research and public health · 2025Article
- Polycystic Ovary Syndrome Underdiagnosis Patterns by Individual-level and Spatial Social Vulnerability Measures.The Journal of clinical endocrinology and metabolism · 2025Article
- Asking Why Is Necessary to Address Health Disparities: A Critical Approach for Solution-Oriented Environmental Epidemiological Research.Environmental health perspectives · 2024Article
- Use of personal care products during pregnancy and birth outcomes - A pilot study.Environmental research · 2023Article
- Racial and ethnic disparities in preterm birth: a mediation analysis incorporating mixtures of polybrominated diphenyl ethers.Frontiers in reproductive health · 2023Article
- Persistent organic pollutant exposure contributes to Black/White differences in leukocyte telomere length in the National Health and Nutrition Examination Survey.Scientific reports · 2022Article
- The Effect of Maternal US Nativity on Racial/Ethnic Differences in Fetal Growth.American journal of epidemiology · 2022Article
- Does early life phthalate exposure mediate racial disparities in children's cognitive abilities?Environmental epidemiology (Philadelphia, Pa.) · 2022Article
- Racial/Ethnic Disparities in Pregnancy and Prenatal Exposure to Endocrine-Disrupting Chemicals Commonly Used in Personal Care Products.Current environmental health reports · 2021Review
- Social Determinants of Health and Diabetes: A Scientific Review.Diabetes care · 2020Review
- Association of self-reported personal care product use with blood glucose levels measured during pregnancy among women from a fertility clinic.The Science of the total environment · 2019Article
Corrections and comments
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Authors and funding
4 authors.
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Abstract
A major goal of health disparities research is to identify and intervene upon modifiable risk factors that help explain the observed associations between social factors and adverse health outcomes. To this end, statistical methods incorporating mediation analysis have shown promise, as they quantify the contribution of an intermediate variable in an exposure-outcome association. A growing body of literature suggests that environmental chemicals can contribute to health disparities. However, evaluating environmental chemicals as an important component of health disparities introduces methodological complexities that may make standard mediation approaches inadequate. Specific to environmental health is the issue of evaluating both the source and biomarker of the environmental toxicant in order to calculate the proportion of the disparity that would remain had we intervened on the modifiable factors. Recent methodological developments on multiple mediators can improve efforts to integrate both source and biomarker of exposure into epidemiological studies of health disparities. We illustrate a conceptual framework and present how mediation techniques can be used to address environmental health disparities questions. With this, we provide a methodological tool that has the potential to advance this growing field, while simultaneously informing public health prevention and policy surrounding the impact of environmental factors on health disparities.
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