Evidence map›Paper›PMID 31531395›Full record

ReviewNPJ digital medicine2019

Enabling Web-scale data integration in biomedicine through Linked Open Data.

Maulik R Kamdar, Javier D Fernández, Axel Polleres, Tania Tudorache, Mark A Musen

Abstract readReview
In one paragraph

Review in NPJ digital medicine, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers.

0numbers the graph read from it
0cells of the map it votes in
12citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

12 citing papers in PubMed.

  1. Review
  2. Article
  3. Article
  4. Article
  5. Article
  6. Article
  7. Review
  8. Article
  9. Article
  10. Article
  11. Article
  12. Text Snippets to Corroborate Medical Relations: An Unsupervised Approach using a Knowledge Graph and Embeddings.AMIA Joint Summits on Translational Science proceedings. AMIA Joint Summits on Translational Science · 2020
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Maulik R Kamdar1Center for Biomedical Informatics Research, Stanford University, Stanford, CA USA.ORCID 0000-0002-9898-0515
Javier D Fernández2Vienna University of Economics & Business, Vienna, Austria.ORCID 0000-0002-2683-827X
Axel Polleres2Vienna University of Economics & Business, Vienna, Austria.
Tania Tudorache1Center for Biomedical Informatics Research, Stanford University, Stanford, CA USA.
Mark A Musen1Center for Biomedical Informatics Research, Stanford University, Stanford, CA USA.

Funding

STANFORD COMPOSITE(RMI)U54HG004028 · NHGRI · STANFORD UNIVERSITY · PI MUSEN, MARK A · 2005 to 2014
$36.2M
Collaborative Development of Biomedical Ontologies and TerminologiesR01GM086587 · NIGMS · STANFORD UNIVERSITY · PI MUSEN, MARK A · 2009 to 2016
$4.1M
Protege: A Knowledge-Engineering Environment for Advancing Biomedical SciencesR01GM121724 · NIGMS · STANFORD UNIVERSITY · PI MUSEN, MARK A · 2017 to 2020
$2.3M
Protege: An Ontology-Development Platform for Biomedical ScientistsR01GM103316 · NIGMS · STANFORD UNIVERSITY · PI MUSEN, MARK A · 2013 to 2016
$2.1M
NHGRI NIH HHS U54 HG004028NIGMS NIH HHS R01 GM086587NIGMS NIH HHS R01 GM103316NIGMS NIH HHS R01 GM121724
6 · The paper itself

Abstract

The biomedical data landscape is fragmented with several isolated, heterogeneous data and knowledge sources, which use varying formats, syntaxes, schemas, and entity notations, existing on the Web. Biomedical researchers face severe logistical and technical challenges to query, integrate, analyze, and visualize data from multiple diverse sources in the context of available biomedical knowledge. Semantic Web technologies and Linked Data principles may aid toward Web-scale semantic processing and data integration in biomedicine. The biomedical research community has been one of the earliest adopters of these technologies and principles to publish data and knowledge on the Web as linked graphs and ontologies, hence creating the Life Sciences Linked Open Data (LSLOD) cloud. In this paper, we provide our perspective on some opportunities proffered by the use of LSLOD to integrate biomedical data and knowledge in three domains: (1) pharmacology, (2) cancer research, and (3) infectious diseases. We will discuss some of the major challenges that hinder the wide-spread use and consumption of LSLOD by the biomedical research community. Finally, we provide a few technical solutions and insights that can address these challenges. Eventually, LSLOD can enable the development of scalable, intelligent infrastructures that support artificial intelligence methods for augmenting human intelligence to achieve better clinical outcomes for patients, to enhance the quality of biomedical research, and to improve our understanding of living systems.

Indexed as

Computational platforms and environmentsDatabasesData integration

Identifiers

PMID31531395
PMCPMC6736878

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.