Evidence map›Paper›PMID 31531357›Full record

ArticleBioMed research international2019

Study on the Effect of Ginsenosides Rb on Blood of Tumor Mice.

Mengmeng Zheng, Wenxiu Zheng, Wei Wang, Hong Guo, Hui Cao, Xiaowei Cui, Shanshan Wang, Chunchao Han

Open access · hybridAbstract read
In one paragraph

Article in BioMed research international, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed, 1 pooled it
0.3field-weighted citation impact, top 40% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 1 synthesis or guideline pooled it, 7 citations in OpenAlex.

  1. Pooled it
  2. Article
  3. Review
  4. Review
  5. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 1 institution in 1 country.

Mengmeng ZhengSchool of Pharmacy, Shandong University of Traditional Chinese Medicine, Jinan 250355, China.
Wenxiu ZhengSchool of Pharmacy, Shandong University of Traditional Chinese Medicine, Jinan 250355, China.ORCID https://orcid.org/0000-0002-3509-8170
Wei WangSchool of Pharmacy, Shandong University of Traditional Chinese Medicine, Jinan 250355, China.
Hong GuoSchool of Pharmacy, Shandong University of Traditional Chinese Medicine, Jinan 250355, China.
Hui CaoSchool of Pharmacy, Shandong University of Traditional Chinese Medicine, Jinan 250355, China.
Xiaowei CuiSchool of Pharmacy, Shandong University of Traditional Chinese Medicine, Jinan 250355, China.
Shanshan WangSchool of Pharmacy, Shandong University of Traditional Chinese Medicine, Jinan 250355, China.
Chunchao HanSchool of Pharmacy, Shandong University of Traditional Chinese Medicine, Jinan 250355, China.ORCID https://orcid.org/0000-0003-2843-7282
Shandong University of Traditional Chinese Medicine · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectiveThe blood of cancer patients is in a state of hypercoagulability, easily leading to thrombosis. Anemia is also a complication of tumors. Anemia and thrombosis affect the treatment of tumor patients.

methodsGinsenosides Rb were extracted from the stems and leaves of American ginseng using water-saturated ethanol and ethyl acetate in silica gel column. Tumor mice model was established by injecting H

resultsThe content of obtained ginsenosides Rb reached 90.05%. This extraction process was simple and reliable. Middle dose of ginsenosides Rb could significantly increase RBC and HGB levels (P<0.05). Moreover, ginsenosides Rb could significantly reduce NLR, PLT, PDW, FIB, and D-D (P<0.01).

conclusionginsenosides Rb could significantly improve anaemia and hypercoagulation of blood in cancer mice. Ginsenosides Rb are a potential anticoagulant and antianemia drug in treating cancer.

Indexed as

AnemiaAnimalsBloodBlood PlateletsCell Line, TumorDisease Models, AnimalErythrocytesFemaleFibrin Fibrinogen Degradation ProductsFibrinogenGinsenosidesHemoglobinsHemostaticsMiceNeoplasmsPanaxFibrin Fibrinogen Degradation Productsfibrin fragment DFibrinogenGinsenosidesHemoglobinsHemostatics

Identifiers

PMID31531357
PMCPMC6720054
OpenAlexW2969048466

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.