ArticleJournal of biomedical physics & engineering2019
Signal Intensity of High B-value Diffusion-weighted Imaging for the Detection of Prostate Cancer.
Article in Journal of biomedical physics & engineering, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.
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3 citing papers in PubMed.
- Accelerated diffusion-weighted imaging of the prostate employing echo planar imaging with compressed SENSE based reconstruction.Scientific reports · 2025Article
- Article
- Diffusion-weighted magnetic resonance imaging at 1.5 T for peripheral zone prostate cancer: the influence of thePolish journal of radiology · 2022Article
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6 authors.
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Abstract
backgroundDiffusion-weighted imaging (DWI) is a main component of multiparametric MRI for prostate cancer detection. Recently, high b value DWI has gained more attention because of its capability for tumor characterization.
objectiveTo assess based on histopathological findings of transrectal ultrasound (TRUS)-guided prostate biopsy as a reference, an increase in signal intensity of prostatic lesions in comparison with normal background tissue on high b-value diffusion-weighted images could be a sign of malignancy. MATERIAL AND
methodsFifty-three consecutive patients retrospectively included in the study. All patients underwent routine TRUS-guided prostate biopsies involving 12 cores after the magnetic resonance imaging (MRI) examinations. In seventeen patients (n =35 lesions), the prostate cancer was histologically confirmed by TRUS-guided prostate biopsy. The biopsy results of other patients were negative. Signal intensities on the high b-value (1600 s/mm
resultsIn the patients with confirmed prostate cancer, fourteen had visually increased SI on the high b-value images. The SI of lesions for these patients was higher than the SI of peripheral zone (22±18%) or central gland (31±20%). In patients with a negative biopsy, eight had visually increased SI on the high b-value images. The SI of lesions for these patients was 23±21% and 35±18% higher than the SI in the peripheral zone and the central gland, respectively. The sensitivity, specificity, PPV, and NPV for prostate cancer using SI of high b value DWI were 71, 87, 62, and 87 %, respectively.
conclusionVisually increased SI on the high b-value images can be an indication of malignancy, although some benign lesions also show this increase in signal intensity.
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