Evidence map›Paper›PMID 31531200›Full record

ArticleACS medicinal chemistry letters2019

Systematically Mitigating the p38α Activity of Triazole-based BET Inhibitors.

Angela S Carlson, Huarui Cui, Anand Divakaran, Jorden A Johnson, Ryan M Brunner, William C K Pomerantz, Joseph J Topczewski

Open access · greenAbstract read
In one paragraph

Article in ACS medicinal chemistry letters, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers.

0numbers the graph read from it
0cells of the map it votes in
13citing papers in PubMed
1.9field-weighted citation impact, top 14% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

13 citing papers in PubMed, 29 citations in OpenAlex.

  1. Review
  2. Article
  3. Review
  4. Review
  5. Article
  6. 4-Methyl-1,2,3-Triazoles asJournal of medicinal chemistry · 2021
    Article
  7. Article
  8. Article
  9. Review
  10. Article
  11. Perfluorocarbons in Chemical Biology.Chembiochem : a European journal of chemical biology · 2020
    Review
  12. Chemical science · 2020
    Article
  13. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 1 institution in 1 country.

Angela S CarlsonDepartment of Chemistry, University of Minnesota Twin Cities, Minneapolis, Minnesota 55455, United States.
Huarui CuiDepartment of Chemistry, University of Minnesota Twin Cities, Minneapolis, Minnesota 55455, United States.
Anand DivakaranDepartment of Chemistry, University of Minnesota Twin Cities, Minneapolis, Minnesota 55455, United States.
Jorden A JohnsonDepartment of Chemistry, University of Minnesota Twin Cities, Minneapolis, Minnesota 55455, United States.
Ryan M BrunnerDepartment of Chemistry, University of Minnesota Twin Cities, Minneapolis, Minnesota 55455, United States.
William C K PomerantzDepartment of Chemistry, University of Minnesota Twin Cities, Minneapolis, Minnesota 55455, United States.
Joseph J TopczewskiDepartment of Chemistry, University of Minnesota Twin Cities, Minneapolis, Minnesota 55455, United States.
University of Minnesota · US

Funding

TRAINING FOR FUTURE BIOTECHNOLOGY DEVELOPMENTT32GM008347 · NIGMS · UNIVERSITY OF MINNESOTA TWIN CITIES · PI SCHMIDT-DANNERT, CLAUDIA · 1990 to 2021
$11.0M
Chemistry-Biology Interface Training GrantT32GM008700 · NIGMS · UNIVERSITY OF MINNESOTA TWIN CITIES · PI DISTEFANO, MARK D · 1999 to 2018
$4.0M
Training the Next Generation of Chemical BiologistsT32GM132029 · NIGMS · UNIVERSITY OF MINNESOTA · PI Erin Elizabeth Carlson, William Charles Krause Pomerantz · 2019 to 2026
$2.7M
Chiral α,α-Disubstituted Amine Synthesis by Dynamic Kinetic ResolutionR35GM124718 · NIGMS · UNIVERSITY OF MINNESOTA · PI TOPCZEWSKI, JOSEPH JOHN · 2017 to 2020
$1.5M
NIGMS NIH HHS R35 GM124718NIGMS NIH HHS T32 GM008347NIGMS NIH HHS T32 GM008700NIGMS NIH HHS T32 GM132029
6 · The paper itself

Abstract

The Bromodomain and Extra Terminal (BET) family of proteins recognize post-translational

Identifiers

PMID31531200
PMCPMC6746085
OpenAlexW2964664658

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.