ReviewCentral-European journal of immunology2019
Melanomacrophages and melanomacrophage centres in
Review in Central-European journal of immunology, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 19 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
19 citing papers in PubMed.
- Nutritional detoxification strategies in aquaculture: bioactive feed additives mitigating oxidative stress and xenobiotic toxicity in fish.Fish physiology and biochemistry · 2026Review
- INHAND: Non-proliferative and proliferative lesions of fish - Chapter 5. Fish hematolymphoid system.Journal of toxicologic pathology · 2026Article
- Resolving the cellular profile of germinal center-analogous microstructures in zebrafish.Frontiers in immunology · 2026Article
- N-Acetylcysteine relieving hydrogen peroxide-induced damage in granulosa cells of sheep.Cell adhesion & migration · 2025Article
- Insights Into Stria Vascular Function, Stria Immunity, and Age-Related Hearing Loss.Journal of the Association for Research in Otolaryngology : JARO · 2025Review
- Anisakid larvae in the organs of Atlantic mackerel,Food and waterborne parasitology · 2025Article
- Dietary transition from pelleted feed to live fry of two brown trout (Salmo trutta) morphs, reared for reintroduction.Scientific reports · 2025Article
- Cellular responses in rainbow trout Oncorhynchus mykiss to experimental Anisakis simplex infection.Parasitology research · 2025Article
- A portrait of 2 nematodes in liver of their paratenic fish hosts, illustrating different immunological approaches.Parasitology · 2025Article
- Amphibian cellular immune response to chytridiomycosis at metamorphic climax.Immunologic research · 2025Article
- Protective immune response in rainbow trout (Frontiers in immunology · 2025Article
- Hepatic melanomacrophage centers in the arctic cultured fishAquaculture (Amsterdam, Netherlands) · 2024Article
- Infection of endemic chubParasitology · 2024Article
- A Window of Vulnerability: Chronic Environmental Stress Does Not Impair Reproduction in the SwordfishAnimals : an open access journal from MDPI · 2023Article
- Teleost innate immunity, an intricate game between immune cells and parasites of fish organs: who wins, who loses.Frontiers in immunology · 2023Review
- Article
- The goldfish Carassius auratus: an emerging animal model for comparative cardiac research.Journal of comparative physiology. B, Biochemical, systemic, and environmental physiology · 2022Review
- PRV-1 Infected Macrophages in Melanized Focal Changes in White Muscle of Atlantic Salmon (Frontiers in immunology · 2021Article
- Assessment of reproductive and developmental effects of graphene oxide on Japanese medaka (Oryzias latipes).Chemosphere · 2020Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
3 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Melanomacrophages (MMs) are phagocytizing cells with high amounts of pigments including melanin which can be found in a number of cold-blooded species. In Osteichthyes, these cells cluster to form so-called melanomacrophage centres (MMCs), which are predominantly present in the stroma of hematopoietic and lymphoid tissues, that is, in the kidney and spleen. The functionality of MMs and MMCs results from their involvement and role in the defence reactions, related to both the innate and the adaptive immune mechanisms, and in processes unrelated to defence functions as well. There is evidence that MMCs are structurally and functionally similar to mammals' germinal centres (GCs). It appears that mature IgM+ B cells in Osteichthyes can be the equivalent of mIgM+ centrocytes in mammals, whereas MMs can be, in terms of the function, the equivalent of follicular dendritic cells (FDCs), and MMCs can be, in terms of clustered specific cells, the equivalent of GCs. This paper presents selected facts about the structural and functional similarity between GCs and MMCs and about the involvement and role of MMCs and MMs in the immune response. The facts help get a proper picture of the location of MMs and MMCs within the structure of the fish immune system, also in the context of their evolutionary relationship with GCs and of the possibility of pointing out the evolutionary closeness between MMCs in Osteichthyes and GCs in mammals.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.