Evidence map›Paper›PMID 31530970›Full record

ArticleJournal of neurolinguistics2019

Differential effect of reading training on functional connectivity in children with reading difficulties with and without ADHD comorbidity.

Tzipi Horowitz-Kraus, Alexander Hershey, Benjamin Kay, Mark DiFrancesco

Abstract read
In one paragraph

Article in Journal of neurolinguistics, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
13citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

13 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Reading Disabilities With and Without Co-Occurring ADHD: No Evidence for Additive Impact on Reading Skills.Scientific studies of reading : the official journal of the Society for the Scientific Study of Reading · 2026
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Tzipi Horowitz-KrausPediatric Neuroimaging Research Consortium, Reading and Literacy Discovery Center, Cincinnati Children's Hospital Medical Center, 3333 Burnett Avenue, Cincinnati, Ohio, United States, 45229.
Alexander HersheyPediatric Neuroimaging Research Consortium, Reading and Literacy Discovery Center, Cincinnati Children's Hospital Medical Center, 3333 Burnett Avenue, Cincinnati, Ohio, United States, 45229.
Benjamin KayPediatric Neuroimaging Research Consortium, Reading and Literacy Discovery Center, Cincinnati Children's Hospital Medical Center, 3333 Burnett Avenue, Cincinnati, Ohio, United States, 45229.
Mark DiFrancescoPediatric Neuroimaging Research Consortium, Reading and Literacy Discovery Center, Cincinnati Children's Hospital Medical Center, 3333 Burnett Avenue, Cincinnati, Ohio, United States, 45229.

Funding

The role of executive functions in reading and reading remediationR01HD086011 · NICHD · HUGO W. MOSER RES INST KENNEDY KRIEGER · PI HOROWITZ-KRAUS, TZIPI · 2016 to 2020
$2.5M
NICHD NIH HHS R01 HD086011
6 · The paper itself

Abstract

A comorbidity of attention deficit hyperactivity disorder (ADHD) with reading difficulties (RD) is common in children. However, children with ADHD+RD have a different reading and executive functions (EF) profile than children with RD alone. We compared the effect of an EF-based intervention on neural circuits related to EF in children with RD and those with ADHD+RD. Functional connectivity MRI data from a lexical decision task suggest that the RD-alone group showed greater improvement in EF and reading tests and greater functional connectivity between networks related to both higher-and lower-level visual processing and those related to ventral attention and dorsal attention, as well as semantic processing. Children with ADHD+RD showed greater connectivity between networks related to attention and dorsal attention and those related to visual processing and EF. Results are consistent with the Cognitive Subtype hypothesis and suggest that RD and ADHD+RD, although related behaviourally, are distinct disorders with regard to network response and connectivity during reading and after an EF-based intervention.

Indexed as

Attention deficit hyperactivity disorderExecutive functionsFunctional connectivityMRIReadingReading difficulties

Identifiers

PMID31530970
PMCPMC6748395

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.