Evidence map›Paper›PMID 31530895›Full record

ArticleScientific reports2019

Activation of 5-HT

Thomas W Flanagan, Melaine N Sebastian, Diana M Battaglia, Timothy P Foster, Emeline L Maillet, Charles D Nichols

Abstract read
In one paragraph

Article in Scientific reports, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 30 papers.

0numbers the graph read from it
0cells of the map it votes in
30citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

30 citing papers in PubMed.

  1. Review
  2. Review
  3. Article
  4. Review
  5. Article
  6. Microdosing Psychedelics to Restore Synaptic Density in Schizophrenia.International journal of molecular sciences · 2025
    Review
  7. Review
  8. 5-HTPharmacological reviews · 2025
    Review
  9. Article
  10. Review
  11. Review
  12. Review
  13. Review
  14. Article
  15. Article
  16. Interval delivery of 5HTJournal of biomedical materials research. Part A · 2023
    Article
  17. Review
  18. Article
  19. Review
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Thomas W FlanaganDepartment of Pharmacology and Experimental Therapeutics Louisiana State University Health Sciences Center 1901 Perdido St, New Orleans, LA, 70112, USA.
Melaine N SebastianDepartment of Pharmacology and Experimental Therapeutics Louisiana State University Health Sciences Center 1901 Perdido St, New Orleans, LA, 70112, USA.
Diana M BattagliaDepartment of Microbiology, Immunology, and Parasitology Louisiana State University Health Sciences Center 1901 Perdido St, New Orleans, LA, 70112, USA.
Timothy P FosterDepartment of Microbiology, Immunology, and Parasitology Louisiana State University Health Sciences Center 1901 Perdido St, New Orleans, LA, 70112, USA.
Emeline L MailletEleusis Benefit Corporation 11 East 44th St., Suite 104, New York, NY, 10017, USA.
Charles D NicholsDepartment of Pharmacology and Experimental Therapeutics Louisiana State University Health Sciences Center 1901 Perdido St, New Orleans, LA, 70112, USA. cnich1@lsuhsc.edu.

Funding

Vascular and Cardiac Function Core - "Mentoring in Cardiovascular BiologyP30GM106392 · NIGMS · LSU HEALTH SCIENCES CENTER · PI KAPUSTA, DANIEL R · 2014 to 2018
$5.5M
NIGMS NIH HHS P30 GM106392
6 · The paper itself

Abstract

Coronary artery disease (CAD) is a progressive cardiovascular syndrome characterized by cholesterol-induced focal arterial lesions that impair oxygen delivery to the heart. As both innate and adaptive immune cells play critical roles in the formation and progression of arterial plaques and endothelial cell dysfunction, CAD is commonly viewed as a chronic inflammatory disorder. Our lab has previously discovered that 5-HT

Indexed as

AmphetaminesAnimalsAnti-Inflammatory Agents, Non-SteroidalAorta, ThoracicBody WeightChemokine CXCL10CholesterolCoronary Artery DiseaseDiet, High-FatDisease Models, AnimalGene Expression RegulationGlucoseMaleMice, Knockout, ApoEReceptors, Serotonin, 5-HT2Serotonin 5-HT2 Receptor Agonists4-iodo-2,5-dimethoxyphenylisopropylamineAmphetaminesAnti-Inflammatory Agents, Non-SteroidalChemokine CXCL10CholesterolCxcl10 protein, mouseGlucoseReceptors, Serotonin, 5-HT2Serotonin 5-HT2 Receptor AgonistsTumor Necrosis Factor-alpha

Identifiers

PMID31530895
PMCPMC6748996

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.