Evidence map›Paper›PMID 31530877›Full record

ArticleScientific reports2019

Surface plasmon resonance immunosensor for label-free detection of BIRC5 biomarker in spontaneously occurring canine mammary tumours.

Subas Chandra Jena, Sameer Shrivastava, Sonal Saxena, Naveen Kumar, Swapan Kumar Maiti, Bishnu Prasad Mishra, Raj Kumar Singh

Open access · goldAbstract read
In one paragraph

Article in Scientific reports, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers.

0numbers the graph read from it
0cells of the map it votes in
12citing papers in PubMed
2.9field-weighted citation impact, top 8% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

12 citing papers in PubMed, 58 citations in OpenAlex.

  1. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 1 institution in 1 country.

Subas Chandra JenaFacility for Research and Training on Bioassays and Biosensor, Division of Veterinary Biotechnology, ICAR-Indian Veterinary Research Institute [Deemed University], Izatnagar 243122, India.
Sameer ShrivastavaFacility for Research and Training on Bioassays and Biosensor, Division of Veterinary Biotechnology, ICAR-Indian Veterinary Research Institute [Deemed University], Izatnagar 243122, India. sameer_vet@rediffmail.com.
Sonal SaxenaFacility for Research and Training on Bioassays and Biosensor, Division of Veterinary Biotechnology, ICAR-Indian Veterinary Research Institute [Deemed University], Izatnagar 243122, India.
Naveen KumarDivision of Surgery, ICAR-Indian Veterinary Research Institute [Deemed University], Izatnagar, 243122, India.
Swapan Kumar MaitiDivision of Surgery, ICAR-Indian Veterinary Research Institute [Deemed University], Izatnagar, 243122, India.
Bishnu Prasad MishraFacility for Research and Training on Bioassays and Biosensor, Division of Veterinary Biotechnology, ICAR-Indian Veterinary Research Institute [Deemed University], Izatnagar 243122, India.
Raj Kumar SinghFacility for Research and Training on Bioassays and Biosensor, Division of Veterinary Biotechnology, ICAR-Indian Veterinary Research Institute [Deemed University], Izatnagar 243122, India.
Indian Veterinary Research Institute · IN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

We report detection of Baculoviral inhibitor of apoptosis repeat containing-5 (BIRC5) protein biomarker in dog serum by label-free surface plasmon resonance (SPR) immunosensor. Initially, overexpression of BIRC5 in canine mammary tumour (CMT) tissues was confirmed by real-time PCR. Recombinant BIRC5 was produced and protein specific antibodies developed in guinea pig specifically reacted with native protein in immunohistochemistry and immunocytochemistry. SPR immunosensor was developed by fabricating anti-BIRC5 antibodies on gold sensor disc. The equilibrium dissociation constant, (K

Indexed as

Biomarkers, TumorSurface Plasmon ResonanceAnimalsBiosensing TechniquesDog DiseasesDogsImmunoassayImmunohistochemistryLimit of DetectionMammary Neoplasms, AnimalPolymerase Chain ReactionRecombinant ProteinsROC CurveSurvivinBiomarkers, TumorRecombinant ProteinsSurvivin

Identifiers

PMID31530877
PMCPMC6748992
OpenAlexW2973732596

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.