Evidence map›Paper›PMID 31530671›Full record

ArticlemBio2019

Lrg1 Regulates β (1,3)-Glucan Masking in Candida albicans through the Cek1 MAP Kinase Pathway.

Tian Chen, Andrew S Wagner, Robert N Tams, James E Eyer, Sarah J Kauffman, Eric R Gann, Elias J Fernandez, Todd B Reynolds

Open access · goldAbstract read
In one paragraph

Article in mBio, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 27 papers.

0numbers the graph read from it
0cells of the map it votes in
27citing papers in PubMed
3.0field-weighted citation impact, top 8% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

27 citing papers in PubMed, 35 citations in OpenAlex.

  1. Loss of Fgr41 inInfection and immunity · 2026
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  4. From Bench to Body: ProtectiveJournal of cellular immunology · 2025
    Article
  5. Disruption tomSphere · 2024
    Article
  6. Article
  7. Article
  8. Baicalin promotes β-1,3-glucan exposure inFrontiers in cellular and infection microbiology · 2024
    Article
  9. Article
  10. Article
  11. Article
  12. Article
  13. Article
  14. Article
  15. Article
  16. Article
  17. Article
  18. Article
  19. Article
  20. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 1 institution in 1 country.

Tian ChenDepartment of Microbiology, The University of Tennessee, Knoxville, Tennessee, USA.
Andrew S WagnerDepartment of Microbiology, The University of Tennessee, Knoxville, Tennessee, USA.
Robert N TamsDepartment of Microbiology, The University of Tennessee, Knoxville, Tennessee, USA.
James E EyerDepartment of Biochemistry & Cellular and Molecular Biology, The University of Tennessee, Knoxville, Tennessee, USA.
Sarah J KauffmanDepartment of Microbiology, The University of Tennessee, Knoxville, Tennessee, USA.
Eric R GannDepartment of Microbiology, The University of Tennessee, Knoxville, Tennessee, USA.
Elias J FernandezDepartment of Biochemistry & Cellular and Molecular Biology, The University of Tennessee, Knoxville, Tennessee, USA.
Todd B ReynoldsDepartment of Microbiology, The University of Tennessee, Knoxville, Tennessee, USA treynol6@utk.edu.
University of Tennessee at Knoxville · US

Funding

Role of Allostery in CAR TransactivationR15GM123469 · NIGMS · UNIVERSITY OF TENNESSEE KNOXVILLE · PI FERNANDEZ, ELIAS J, MCCORD, RACHEL PATTON · 2017 to 2017
$453k
Identification of CDP-DAG and serine binding sites in Candida albicans phosphatidylserine synthase, an antifungal drug targetR21AI130895 · NIAID · UNIVERSITY OF TENNESSEE KNOXVILLE · PI REYNOLDS, TODD B · 2017 to 2018
$409k
NIAID NIH HHS R21 AI130895NIGMS NIH HHS R15 GM123469
6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

Gene Expression Regulation, FungalMAP Kinase Signaling SystemAnimalsCandida albicansFungal ProteinsMaleMiceMice, Inbred ICRMitogen-Activated Protein Kinase 3VirulenceCEK1 protein, Candida albicansFungal ProteinsMitogen-Activated Protein Kinase 3Candida albicansCdc42Cek1cell wallGTPaseMAPK cascadeRac1Ras1Rho1Ste11virulenceβ (1,3)-glucan

Identifiers

PMID31530671
PMCPMC6751057
OpenAlexW2973869548

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.