Evidence map›Paper›PMID 31530668›Full record

ArticlemBio2019

A Novel Tool for the Generation of Conditional Knockouts To Study Gene Function across the Plasmodium falciparum Life Cycle.

Marta Tibúrcio, Annie S P Yang, Kazuhide Yahata, Pablo Suárez-Cortés, Hugo Belda, Sebastian Baumgarten, Marga van de Vegte-Bolmer, Geert-Jan van Gemert, Youri van Waardenburg, Elena A Levashina and 2 more

Open access · goldAbstract read
In one paragraph

Article in mBio, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 44 papers.

0numbers the graph read from it
0cells of the map it votes in
44citing papers in PubMed
7.5field-weighted citation impact, top 2% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

44 citing papers in PubMed, 81 citations in OpenAlex.

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  7. The CLAMP-Linked Invasion Protein (CLIP) plays an essential role inbioRxiv : the preprint server for biology · 2026
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  9. The essential function of the apical polar ring during the blood stage ofbioRxiv : the preprint server for biology · 2026
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  16. Systematic in vitro evolution inScience (New York, N.Y.) · 2024
    Article
  17. ThemSphere · 2024
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  20. The threemSphere · 2024
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors at 6 institutions in 5 countries.

Marta TibúrcioSignalling in Apicomplexan Parasites Laboratory, The Francis Crick Institute, London, United Kingdom.
Annie S P YangDepartment of Medical Microbiology, Radboud University Medical Centre, Nijmegen, Netherlands.
Kazuhide YahataSignalling in Apicomplexan Parasites Laboratory, The Francis Crick Institute, London, United Kingdom.
Pablo Suárez-CortésVector Biology Unit, Max Planck Institute for Infection Biology, Berlin, Germany.
Hugo BeldaSignalling in Apicomplexan Parasites Laboratory, The Francis Crick Institute, London, United Kingdom.
Sebastian BaumgartenBiology of Host-Parasite Interactions Unit, Institut Pasteur, Paris, France.
Marga van de Vegte-BolmerDepartment of Medical Microbiology, Radboud University Medical Centre, Nijmegen, Netherlands.
Geert-Jan van GemertDepartment of Medical Microbiology, Radboud University Medical Centre, Nijmegen, Netherlands.
Youri van WaardenburgDepartment of Medical Microbiology, Radboud University Medical Centre, Nijmegen, Netherlands.
Elena A LevashinaVector Biology Unit, Max Planck Institute for Infection Biology, Berlin, Germany.
Robert W SauerweinDepartment of Medical Microbiology, Radboud University Medical Centre, Nijmegen, Netherlands.
Moritz TreeckSignalling in Apicomplexan Parasites Laboratory, The Francis Crick Institute, London, United Kingdom moritz.treeck@crick.ac.uk.
Radboud University Nijmegen · NLThe Francis Crick Institute · GBMax Planck Institute for Infection Biology · DERadboud University Medical Center · NLInstitut Pasteur · FRNagasaki University · JP

Funding

Cancer Research UK FC001189Medical Research Council FC001189Wellcome Trust FC001189
6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

Gene DeletionGenes, ProtozoanGene Knockout TechniquesIntegrasesLife Cycle StagesMolecular BiologyMosquito VectorsPhenotypePlasmodium falciparumSirolimusCre recombinaseIntegrasesSirolimusmalariamolecular methodsPlasmodium falciparumreverse genetic analysis

Identifiers

PMID31530668
PMCPMC6751054
OpenAlexW2974812166

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.