Evidence map›Paper›PMID 31530643›Full record

ArticleThe Journal of neuroscience : the official journal of the Society for Neuroscience2019

RIMB-1/RIM-Binding Protein and UNC-10/RIM Redundantly Regulate Presynaptic Localization of the Voltage-Gated Calcium Channel in

Yuto Kushibiki, Toshiharu Suzuki, Yishi Jin, Hidenori Taru

Open access · bronzeAbstract read
In one paragraph

Article in The Journal of neuroscience : the official journal of the Society for Neuroscience, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 33 papers.

0numbers the graph read from it
0cells of the map it votes in
33citing papers in PubMed
2.5field-weighted citation impact, top 11% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

33 citing papers in PubMed, 53 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
  4. Article
  5. Article
  6. Review
  7. Article
  8. Article
  9. RIM and RIM-Binding Protein Localize Synaptic CaV2 Channels to Differentially Regulate Transmission in Neuronal Circuits.The Journal of neuroscience : the official journal of the Society for Neuroscience · 2024
    Article
  10. Article
  11. Article
  12. Article
  13. The role of specific isoforms of CaScientific reports · 2023
    Article
  14. Proceedings of the National Academy of Sciences of the United States of America · 2023
    Article
  15. Article
  16. Presynaptic Cytomatrix Proteins.Advances in neurobiology · 2023
    Article
  17. Article
  18. Article
  19. Article
  20. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 2 institutions in 2 countries.

Yuto KushibikiLaboratory of Neuroscience, Graduate School of Pharmaceutical Sciences, Hokkaido University, Sapporo 060-0812, Japan, and.
Toshiharu SuzukiLaboratory of Neuroscience, Graduate School of Pharmaceutical Sciences, Hokkaido University, Sapporo 060-0812, Japan, and.ORCID 0000-0002-1655-2374
Yishi JinNeurobiology Section, Division of Biological Sciences, University of California, San Diego, La Jolla, California 92093.ORCID 0000-0002-9371-9860
Hidenori TaruLaboratory of Neuroscience, Graduate School of Pharmaceutical Sciences, Hokkaido University, Sapporo 060-0812, Japan, and taru@pharm.hokudai.ac.jp.ORCID 0000-0002-3773-2614
Hokkaido University · JPUniversity of California San Diego · US

Funding

Enhancing and expanding the CGC Strain CollectionP40OD010440 · OD · UNIVERSITY OF MINNESOTA · PI Aric L Daul, Ann E. Rougvie · 2012 to 2026
$7.5M
GABAERGIC NEURON DIFFERENTIATION IN C ELEGANSR01NS035546 · NINDS · UNIVERSITY OF CALIFORNIA SANTA CRUZ · PI JIN, YISHI · 1996 to 2016
$5.3M
GABAergic Neuron Differentiation in C.elegansR37NS035546 · NINDS · UNIVERSITY OF CALIFORNIA, SAN DIEGO · PI JIN, YISHI · 2017 to 2021
$2.4M
NIH HHS P40 OD010440NINDS NIH HHS R01 NS035546NINDS NIH HHS R37 NS035546
6 · The paper itself

Abstract

Presynaptic active zones (AZs) contain many molecules essential for neurotransmitter release and are assembled in a highly organized manner. A network of adaptor proteins known as cytomatrix at the AZ (CAZ) is important for shaping the structural characteristics of AZ. Rab3-interacting molecule (RIM)-binding protein (RBP) family are binding partners of the CAZ protein RIM and also bind the voltage-gated calcium channels (VGCCs) in mice and flies. Here, we investigated the physiological roles of RIMB-1, the homolog of RBPs in the nematode

Indexed as

AnimalsAnimals, Genetically ModifiedCaenorhabditis elegansCaenorhabditis elegans ProteinsCalcium Channels, P-TypeCalcium Channels, Q-TypeCarrier ProteinsIntracellular Signaling Peptides and ProteinsNeuronsPresynaptic TerminalsCaenorhabditis elegans ProteinsCalcium Channels, P-TypeCalcium Channels, Q-TypeCarrier ProteinsIntracellular Signaling Peptides and Proteinsrimb-1 protein, C elegansunc-10 protein, C elegansactive zoneadaptor proteinC. elegansgenetic interactionpresynapsevoltage-gated calcium channel

Identifiers

PMID31530643
PMCPMC6820209
OpenAlexW2974363127

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.