ArticleThe Journal of biological chemistry2019
Structural and functional aspects of mannuronic acid-specific PL6 alginate lyase from the human gut microbe
Article in The Journal of biological chemistry, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 23 papers.
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Who cites it
23 citing papers in PubMed, 77 citations in OpenAlex.
- The Effects of Dietary Fiber and High-Dietary-Fiber Diets on Body Weight Regulation and Lipid Metabolism in Athletes: A Narrative Review.Nutrients · 2026Review
- Cloning and Characterization of a PL6 Alginate Lyase Aly94 from the Marine Bacteria.Molecular biotechnology · 2026Article
- Dissecting a two-domain alginate lyase of family PL6 reveals a mechanistic basis for substrate specificity and enzyme activity.The Journal of biological chemistry · 2026Article
- Alginate oligosaccharides derived from tropical brown seaweeds as sustainable alternatives to antibiotic growth promoters in poultry nutrition: Functional mechanisms and production perspectives.Veterinary world · 2026Review
- Alginate oligosaccharides in the food industry: emerging functional roles, health benefits, and technological applications - Review.Food chemistry: X · 2025Review
- Review
- Characterization of a novel alginate lyase Alg0392 with organic solvent-tolerance from Alteromonas sp. A1-6.Applied microbiology and biotechnology · 2025Article
- Bone Defect Treatment in Regenerative Medicine: Exploring Natural and Synthetic Bone Substitutes.International journal of molecular sciences · 2025Review
- Review
- Polysaccharides and oligosaccharides originated from green algae: structure, extraction, purification, activity and applications.Bioresources and bioprocessing · 2024Review
- Exploring potential polysaccharide utilization loci involved in the degradation of typical marine seaweed polysaccharides byFrontiers in microbiology · 2024Article
- Three alginate lyases provide a new gutApplied and environmental microbiology · 2023Article
- Ulvan and Ulva oligosaccharides: a systematic review of structure, preparation, biological activities and applications.Bioresources and bioprocessing · 2023Review
- Human Gut Microbiota and Drug Metabolism.Microbial ecology · 2023Review
- Characterization of degradation patterns and enzymatic properties of a novel alkali-resistant alginate lyase AlyRm1 fromCurrent research in food science · 2023Article
- Dissecting the essential role of N-glycosylation in catalytic performance of xanthan lyase.Bioresources and bioprocessing · 2022Article
- Cloning and Characterization of a Novel Alginate Lyase fromMarine drugs · 2022Article
- Structure Characteristics, Biochemical Properties, and Pharmaceutical Applications of Alginate Lyases.Marine drugs · 2021Review
- Plant-Based Diet Index and Metabolic Risk in Men: Exploring the Role of the Gut Microbiome.The Journal of nutrition · 2021Article
- Biochemical Characterization of a Novel Exo-Type PL7 Alginate Lyase VsAly7D from MarineInternational journal of molecular sciences · 2021Article
Corrections and comments
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Authors and funding
11 authors at 3 institutions in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Alginate is a linear polysaccharide from brown algae consisting of 1,4-linked β-d-mannuronic acid (M) and α-l-guluronic acid (G) arranged in M, G, and mixed MG blocks. Alginate was assumed to be indigestible in humans, but bacteria isolated from fecal samples can utilize alginate. Moreover, genomes of some human gut microbiome-associated bacteria encode putative alginate-degrading enzymes. Here, we genome-mined a polysaccharide lyase family 6 alginate lyase from the gut bacterium
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.