ArticleBMJ open2019
Mortality and cause of death in South Korean patients with Parkinson's disease: a longitudinal follow-up study using a national sample cohort.
Article in BMJ open, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers, 1 of them a synthesis that pooled it.
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Who cites it
15 citing papers in PubMed, 1 synthesis or guideline pooled it, 23 citations in OpenAlex.
- Case Definitions and Data Sources for NNCSS Parkinson Disease Surveillance: A Systematic Review.JAMA network open · 2026Pooled it
- Effects of Liuzijue Qigong on respiratory function among patients with Parkinson's disease: a randomized clinical trial.BMC complementary medicine and therapies · 2025Trial
- Acupuncture-Related Therapies as a Potential Adjuvant Option for Parkinson's Disease: Effects on Symptom Management, Medication Use, and Mortality.Parkinson's disease · 2026Article
- Mortality risk associated with acetylcholinesterase inhibitor use in Parkinson's disease dementia according to sex and age at disease onset: a nationwide cohort study.Epidemiology and health · 2026Article
- Far from being the end of the road: taking a closer look at neuropalliative care in Parkinson's disease.Journal of neural transmission (Vienna, Austria : 1996) · 2025Review
- Mortality and causes of death in patients with Parkinson's disease in Taiwan.Journal of Parkinson's disease · 2025Article
- The Potentiality of Natural Products and Herbal Medicine as Novel Medications for Parkinson's Disease: A Promising Therapeutic Approach.International journal of molecular sciences · 2024Review
- Association between smoking and all-cause mortality in Parkinson's disease.NPJ Parkinson's disease · 2023Article
- Longitudinal follow-up study of the association with gout and Alzheimer's disease and Parkinson's disease in Korea.Scientific reports · 2023Article
- Parkinson's disease clinical milestones and mortality.NPJ Parkinson's disease · 2022Article
- Causes of Mortality in Korean Patients with Neurodegenerative Dementia.BioMed research international · 2022Article
- The Association of Pre-existing Diagnoses of Alzheimer's Disease and Parkinson's Disease and Coronavirus Disease 2019 Infection, Severity and Mortality: Results From the Korean National Health Insurance Database.Frontiers in aging neuroscience · 2022Article
- The Association between Anemia and Parkinson's Disease: A Nested Case-Control Study Using a National Health Screening Cohort.Brain sciences · 2021Article
- The Occurrence of Alzheimer's Disease and Parkinson's Disease in Individuals With Osteoporosis: A Longitudinal Follow-Up Study Using a National Health Screening Database in Korea.Frontiers in aging neuroscience · 2021Article
- Mortality and cause of death in physical activity and insufficient physical activity participants: a longitudinal follow-up study using a national health screening cohort.BMC public health · 2020Article
Corrections and comments
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Authors and funding
5 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
objectiveThe incidence rate of Parkinson's disease (PD) is growing rapidly owing to the ageing population. We investigated the mortality rates and causes of death in South Korean patients with PD.
designWe investigated a national cohort using the nationwide insurance database.
settingKorean Health Insurance Review and Assessment Service-National Sample Cohort database.
participantsWe included 3510 participants ≥60 years of age who were diagnosed with PD between 2002 and 2013, as well as 14 040 matched controls.
interventionsNone PRIMARY AND SECONDARY OUTCOME MEASURES: A stratified Cox proportional hazards model was used to evaluate patients with PD who were matched 1:4 with non-PD control subjects adjusted for age, sex, income and region of residence. The causes of death were grouped into 12 classifications.
resultsThe adjusted HR for mortality in the PD group was 2.09 (95% CI 1.94 to 2.24, p<0.001). Subgroup analysis according to age (<70 years, 70-79 years, and ≥80 years) and sex revealed that patients with PD showed higher adjusted HRs for mortality across all subgroups. Mortalities caused by metabolic, mental, neurologic, circulatory, respiratory, and genitourinary diseases, as well as trauma, were more common in the PD group than in the control group, with the highest OR observed in patients with neurologic disease.
conclusionsWe demonstrated that PD in South Korean patients ≥60 years of age was associated with increased mortality in both sexes regardless of age.
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