Evidence map›Paper›PMID 31530594›Full record

ArticleBMJ open2019

Association between carotid intima-media thickness and bone mineral density: a cross-sectional study in Vietnamese men and women aged 50 years and older.

Lich T Nguyen, Vinh N Pham, Phuong M N Chau, Lan T Ho-Pham, Tuan V Nguyen

Abstract read
In one paragraph

Article in BMJ open, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Lich T NguyenBone and Muscle Research Group, Ton Duc Thang University, Ho Chi Minh City, Vietnam.
Vinh N PhamTam Duc Heart Hospital, Ho Chi Minh City, Vietnam.
Phuong M N ChauBone and Muscle Research Group, Ton Duc Thang University, Ho Chi Minh City, Vietnam.
Lan T Ho-PhamBone and Muscle Research Group, Ton Duc Thang University, Ho Chi Minh City, Vietnam hophamthuclan@tdt.edu.vn.
Tuan V NguyenBone Biology Division, Garvan Institute of Medical Research, Sydney, New South Wales, Australia.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectivesThe association between osteoporosis and atherosclerosis remains controversial. We sought to define the relationship between carotid intima-media thickness and bone mineral density (BMD) in individuals of Vietnamese background. DESIGN AND

settingCross-sectional study in Ho Chi Minh City, Vietnam.

participantsThe study involved 1460 individuals (559 men) aged 50 years and older (average age 59 years) who were randomly recruited from the community. OUTCOME MEASURES: BMD at the femoral neck and lumbar spine was measured by dual-energy X-ray absorptiometry (Hologic, Waltham, Massachusetts, USA). Carotid intima-media thickness (cIMT) was measured using a Philips Ultrasonography (HD7XE). The presence of atherosclerotic plaque was ascertained for each individual. The association between cIMT and BMD was analysed by a multiple linear regression model.

resultsIn unadjusted analysis, cIMT was positively associated with femoral neck BMD in men (p=0.005), but not in women (p=0.242). After adjusting for age, smoking, diabetes and hypertension, the association remained statistically significant in men (partial R

conclusionsIn Vietnamese individuals aged 50 years and older, there is a clinically non-significant but statistically significant association between carotid intima-media thickness and BMD in men, not in women.

Indexed as

Bone DensityCarotid Intima-Media ThicknessAbsorptiometry, PhotonAgedAged, 80 and overCarotid ArteriesCross-Sectional StudiesFemaleFemur NeckHumansLinear ModelsLumbar VertebraeMaleMiddle AgedSex FactorsUltrasonographyAtherosclerosisBone mineral densityCarotid intima media thicknessOsteoporosisVietnam osteoporosis study

Identifiers

PMID31530594
PMCPMC6756441

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.