Evidence map›Paper›PMID 31530037›Full record

ArticleConnective tissue research2020

Naturally occurring osteoarthritis in male mice with an extended lifespan.

Dave Ewart, Lindsey Harper, Amy Gravely, Richard A Miller, Cathy S Carlson, Richard F Loeser

Open access · greenAbstract readVideo-Audio Media
In one paragraph

Article in Connective tissue research, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed, 1 pooled it
1.3field-weighted citation impact, top 20% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed, 1 synthesis or guideline pooled it, 33 citations in OpenAlex.

  1. Pooled it
  2. Article
  3. Article
  4. Article
  5. Article
  6. Review
  7. Cartilage-specificAnnals of the rheumatic diseases · 2023
    Article
  8. Article
  9. Geroprotectors and Skeletal Health: Beyond the Headlines.Frontiers in cell and developmental biology · 2022
    Review
  10. Article
  11. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 3 institutions in 1 country.

Dave EwartDivision of Rheumatology, Minneapolis Veterans Affairs Medical Center, Minneapolis, MN, USA.
Lindsey HarperDepartment of Veterinary Clinical Sciences, Veterinary Medical Center, St. Paul, MN, USA.
Amy GravelyDivision of Rheumatology, Minneapolis Veterans Affairs Medical Center, Minneapolis, MN, USA.
Richard A MillerDepartment of Pathology, University of Michigan School of Medicine, Ann Arbor, MI, USA.
Cathy S CarlsonDepartment of Veterinary Clinical Sciences, Veterinary Medical Center, St. Paul, MN, USA.
Richard F LoeserDivision of Rheumatology, Allergy and Immunology and the Thurston Arthritis Research Center, University of North Carolina, Chapel Hill, NC, USA.
Veterans Health Administration · USUniversity of Michigan–Ann Arbor · USUniversity of North Carolina at Chapel Hill · US

Funding

Systems BiologyU19AG023122 · NIA · TRANSLATIONAL GENOMICS RESEARCH INST · PI NICHOLAS Joseph SCHORK · 2004 to 2026
$102.6M
Research Education CoreP30AG024824 · NIA · UNIVERSITY OF MICHIGAN AT ANN ARBOR · PI Andrzej T Galecki · 2004 to 2026
$29.2M
Laboratory for Anti-Geric Testing, Evaluation and ResearchU01AG022303 · NIA · UNIVERSITY OF MICHIGAN AT ANN ARBOR · PI RICHARD A MILLER · 2003 to 2026
$25.4M
Oxidative Stress and the Development of OsteoarthritisR01AG044034 · NIA · WAKE FOREST UNIVERSITY HEALTH SCIENCES · PI RICHARD F LOESER · 2012 to 2026
$5.7M
NIA NIH HHS P30 AG024824NIA NIH HHS R01 AG044034NIA NIH HHS U01 AG022303NIA NIH HHS U19 AG023122
6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

LongevityAnimalsEstradiolMaleMiceMice, KnockoutOsteoarthritisEstradiolagingcartilagehealthspanlifespanOsteoarthritis

Identifiers

PMID31530037
PMCPMC6884676
OpenAlexW2974575261

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.