Evidence map›Paper›PMID 31530032›Full record

ArticleJournal of enzyme inhibition and medicinal chemistry2019

Synthesis and

Wei-Yun Guo, Liu-Zeng Chen, Bang-Nian Shen, Xin-Hua Liu, Guang-Ping Tai, Qing-Shan Li, Li Gao, Ban-Feng Ruan

Abstract read
In one paragraph

Article in Journal of enzyme inhibition and medicinal chemistry, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Article
  2. Article
  3. 1,4-Disubstituted 1International journal of molecular sciences · 2020
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Wei-Yun GuoSchool of Food and Biological Engineering, Hefei University of Technology , Hefei , PR China.
Liu-Zeng ChenSchool of Pharmacy, Anhui Province Key Laboratory of Major Autoimmune Diseases, Anhui Medical University , Hefei , PR China.
Bang-Nian ShenSchool of Food and Biological Engineering, Hefei University of Technology , Hefei , PR China.
Xin-Hua LiuSchool of Pharmacy, Anhui Province Key Laboratory of Major Autoimmune Diseases, Anhui Medical University , Hefei , PR China.
Guang-Ping TaiKey Lab of Biofabrication of Anhui Higher Education Institution Centre for Advanced Biofabrication, Hefei University , Hefei , PR China.
Qing-Shan LiSchool of Food and Biological Engineering, Hefei University of Technology , Hefei , PR China.
Li GaoSchool of Food and Biological Engineering, Hefei University of Technology , Hefei , PR China.
Ban-Feng RuanSchool of Food and Biological Engineering, Hefei University of Technology , Hefei , PR China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

A series of novel 4-ferrocenylchroman-2-one derivatives were designed and synthesised to discover potent anti-inflammatory agents for treatment of arthritis. All the target compounds had been screened for their anti-inflammatory activity by evaluating the inhibition effect of LPS-induced NO production in RAW 264.7 macrophages. Among them, 4-ferrocenyl-3,4-dihydro-2H-benzo[

Indexed as

Interleukin-6 InhibitorsAnimalsAnti-Inflammatory Agents, Non-SteroidalArthritisCell SurvivalChromonesDose-Response Relationship, DrugFreund's AdjuvantInterleukin-6LipopolysaccharidesMaleMiceMitogen-Activated Protein KinasesMolecular StructureNF-kappa BRatsAnti-Inflammatory Agents, Non-SteroidalChromonesFreund's AdjuvantInterleukin-6Interleukin-6 Inhibitorsinterleukin-6, mouseLipopolysaccharidesMitogen-Activated Protein KinasesNF-kappa BTumor Necrosis Factor-alphaanti-inflammatory activitychroman-2-onedesignFerrocenesynthesis

Identifiers

PMID31530032
PMCPMC6758610

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.