Evidence map›Paper›PMID 31529692›Full record

ArticleNeuropsychopharmacology reports2019

Bee honey protects astrocytes against oxidative stress: A preliminary in vitro investigation.

Amira Mohammed Ali, Hiroshi Kunugi

Open access · goldAbstract read
In one paragraph

Article in Neuropsychopharmacology reports, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 21 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
21citing papers in PubMed, 1 pooled it
6.6field-weighted citation impact, top 3% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

21 citing papers in PubMed, 1 synthesis or guideline pooled it, 44 citations in OpenAlex.

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  10. Approaches to Nutritional Screening in Patients with Coronavirus Disease 2019 (COVID-19).International journal of environmental research and public health · 2021
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  18. Psychological Climacteric Symptoms and Attitudes toward Menopause among Emirati Women.International journal of environmental research and public health · 2020
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors at 1 institution in 2 countries.

Amira Mohammed AliDepartment of Mental Disorder Research, National Center of Neurology and Psychiatry, National Institute of Neuroscience, Tokyo, Japan.ORCID 0000-0002-6448-8282
Hiroshi KunugiDepartment of Mental Disorder Research, National Center of Neurology and Psychiatry, National Institute of Neuroscience, Tokyo, Japan.ORCID 0000-0002-7209-3790
National Center of Neurology and Psychiatry · JP

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

aimBee honey is widely used as a bioactive food to improve general health and produce therapeutic benefits in various physical disorders. It also improves cognitive and mood-related behaviors and symptoms in mice and humans. Still, its direct effect on brain cells is unclear. Here, we examined the effect of whole honey on the survival of astrocytes exposed to oxidative stress.

methodsCultured cortical astrocytes were treated with honey (0.1%, 0.3%, 0.5%, 0.6%, 0.7%, 0.8%, 0.9%, 1%, 3%, and 5% [v/v]) for 24 hours followed by H

resultsHoney prevented cellular death in a dose-dependent manner compared with H

conclusionBee honey exerts a neuroprotective effect through its antioxidant activity.

Indexed as

HoneyAnimalsAntioxidantsAstrocytesCerebral CortexHydrogen PeroxideNeuroprotective AgentsOxidative StressRatsRats, WistarAntioxidantsHydrogen PeroxideNeuroprotective Agentsastrocytesbee honeyneuroinflammationneuropsychiatric disordersoxidative stress

Identifiers

PMID31529692
PMCPMC7292328
OpenAlexW2974060581

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.