ReviewActa obstetricia et gynecologica Scandinavica2020
Gastric cancer during pregnancy: A report on 13 cases and review of the literature with focus on chemotherapy during pregnancy.
Review in Acta obstetricia et gynecologica Scandinavica, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 20 papers.
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Who cites it
20 citing papers in PubMed, 29 citations in OpenAlex.
- Diagnostic and treatment delay in women with cancer in pregnancy: a case-based study.Archives of gynecology and obstetrics · 2026Article
- Successful Spontaneous Twin Pregnancy Following Bone Marrow Transplant and Gastric Cancer Surgery: A Case Report.The American journal of case reports · 2026Article
- Gastric cancer in pregnancy: A case report.Oncology letters · 2026Article
- Article
- Upper Gastrointestinal Tumors during Pregnancy: Diagnosis, Risk Factors, and Treatment Options - A Literature Review.Visceral medicine · 2025Review
- Review
- CAnceR IN PreGnancy (CARING) - a retrospective study of cancer diagnosed during pregnancy in the United Kingdom.British journal of cancer · 2024Article
- Pregnancy and Gastric Cancer: A Narrative Review.Diagnostics (Basel, Switzerland) · 2023Review
- Prognosis, counseling, and indications for termination of pregnancy.Abdominal radiology (New York) · 2023Review
- Fetal and placental metastases associated with maternal cancers.Abdominal radiology (New York) · 2023Review
- Gastrointestinal malignancies in pregnancy.Abdominal radiology (New York) · 2023Review
- The challenging presentation of gastric cancer during pregnancy with krukenberg tumor: a case report.Annals of medicine and surgery (2012) · 2023Article
- Aggressive Intestinal Symptoms Caused by Metastatic Tumors Originating from Primary Gastric Cancer in Pregnancy: A Case Report.Maternal-fetal medicine (Wolters Kluwer Health, Inc.) · 2023Article
- Tumorigenic mechanisms of estrogen and Helicobacter pylori cytotoxin-associated gene A in estrogen receptor α-positive diffuse-type gastric adenocarcinoma.Gastric cancer : official journal of the International Gastric Cancer Association and the Japanese Gastric Cancer Association · 2022Article
- Efficacy and Safety of Platinum-Based Chemotherapy for Ovarian Cancer During Pregnancy: A Systematic Review and Meta-Analysis.Oncology and therapy · 2022Review
- Hepatoid adenocarcinoma of the stomach with PIK3Ca mutation during pregnancy: A case report with molecular profile.Oxford medical case reports · 2021Article
- Long-Term Neurodevelopmental Outcome of Children after in Utero Exposure to Chemotherapy.Cancers · 2020Review
- Postpartum Involution and Cancer: An Opportunity for Targeted Breast Cancer Prevention and Treatments?Cancer research · 2020Review
- Gastric cancer during pregnancy: A report on 13 cases and review of the literature with focus on chemotherapy during pregnancy.Acta obstetricia et gynecologica Scandinavica · 2020Review
- Krukenberg Tumor of Gastric Origin in Pregnant Women with Preeclampsia.Case reports in oncologyArticle
Corrections and comments
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Authors and funding
14 authors at 10 institutions in 6 countries.
Funding
Abstract
introductionGastric cancer during pregnancy is extremely rare and data on optimal treatment and possible chemotherapeutic regimens are scarce. The aim of this study is to describe the obstetric and maternal outcome of women with gastric cancer during pregnancy and review the literature on antenatal chemotherapy for gastric cancer. MATERIAL AND
methodsTreatment and outcome of patients registered in the International Network on Cancer, Infertility and Pregnancy database with gastric cancer diagnosed during pregnancy were analyzed.
resultsIn total, 13 women with gastric cancer during pregnancy were registered between 2002 and 2018. Median gestational age at diagnosis was 22 weeks (range 6-30 weeks). Twelve women were diagnosed with advanced disease and died within 2 years after pregnancy, most within 6 months. In total, eight out of 10 live births ended in a preterm delivery because of preeclampsia, maternal deterioration, or therapy planning. Two out of six women who initiated chemotherapy during pregnancy delivered at term. Two neonates prenatally exposed to chemotherapy were growth restricted and one of them developed a systemic infection with brain abscess after preterm delivery for preeclampsia 2 weeks after chemotherapy. No malformations were reported.
conclusionsThe prognosis of gastric cancer during pregnancy is poor, mainly due to advanced disease at diagnosis, emphasizing the need for early diagnosis. Antenatal chemotherapy can be considered to reach fetal maturity, taking possible complications such as growth restriction, preterm delivery, and hematopoietic suppression at birth into account.
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