Evidence map›Paper›PMID 31529401›Full record

ArticleLa Radiologia medica2020

Gray matter nuclei damage in acute carbon monoxide intoxication assessed in vivo using diffusion tensor MR imaging.

Wenqian Jiang, Qingyu Wu, Chun Zhou, Ziru Zhao, Yongming Tan

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Article in La Radiologia medica, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
0.3field-weighted citation impact, top 40% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 13 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 1 institution in 1 country.

Wenqian JiangDepartment of Radiology, The First Affiliated Hospital of Nanchang University, Yongwaizheng Street 17, Nanchang, 330006, Jiangxi Province, China.
Qingyu WuDepartment of Radiology, The First Affiliated Hospital of Nanchang University, Yongwaizheng Street 17, Nanchang, 330006, Jiangxi Province, China.
Chun ZhouDepartment of Radiology, The First Affiliated Hospital of Nanchang University, Yongwaizheng Street 17, Nanchang, 330006, Jiangxi Province, China.
Ziru ZhaoDepartment of Radiology, The First Affiliated Hospital of Nanchang University, Yongwaizheng Street 17, Nanchang, 330006, Jiangxi Province, China.
Yongming TanDepartment of Radiology, The First Affiliated Hospital of Nanchang University, Yongwaizheng Street 17, Nanchang, 330006, Jiangxi Province, China. tanyongming1209@163.com.ORCID http://orcid.org/0000-0002-0650-3763
Nanchang University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectiveTo observe the structural changes of gray matter nuclei in patients with acute carbon monoxide intoxication by diffusion tensor imaging (DTI), quantify the degree of deep gray matter damage in the brain by adopting imaging technology and research the characteristics of the damage and its pertinence with memory and cognitive impairment.

methodsTwenty-five patients with acute carbon monoxide intoxication and 25 healthy volunteers matched in sex and age were examined by routine head MRI and diffusion tensor imaging (DTI). Bilateral hippocampus, dater nucleus, thalamus, amygdala, globus pallidus and putamen were taken as regions of interest. The mean diffusion coefficient (MD), anisotropic fraction (FA) and appearance of deep gray matter nucleus in patients with acute carbon monoxide intoxication were analyzed. It found that the change of diffusion coefficient (ADC) and its clinical correlation with cognitive impairment were generated by carbon monoxide intoxication.

resultsCompared with the healthy control group, the FA values of bilateral globus pallidus, hippocampus, dater nucleus and putamen decreased, while the FA values of amygdala and thalamus had no statistical significance; the MD values and ADC values of hippocampus, globus pallidus and putamen increased, while the MD and ADC values of dater nucleus, thalamus and amygdala had no statistical significance, either.

conclusionDTI is capable of sensitively reflecting the damage of gray matter nuclei caused by acute carbon monoxide intoxication and quantifying the degree of hypoxic brain damage in a certain extent, and may be related to cognitive impairment.

Indexed as

Acute DiseaseAdultAgedAmygdalaAnisotropyBrain Injuries, DiffuseCarbon Monoxide PoisoningCase-Control StudiesCognitionDiffusion Tensor ImagingFemaleGlobus PallidusGray MatterHippocampusHumansMagnetic Resonance ImagingAcute carbon monoxide intoxicationAnisotropic fractionApparent diffusion coefficientAverage diffusion coefficientGray matter nucleus

Identifiers

PMID31529401
OpenAlexW2974609323

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.