Evidence map›Paper›PMID 31529264›Full record

ArticleEuropean journal of nuclear medicine and molecular imaging2020

Integration of dynamic parameters in the analysis of

Merwan Ginet, Timothée Zaragori, Pierre-Yves Marie, Véronique Roch, Guillaume Gauchotte, Fabien Rech, Marie Blonski, Zohra Lamiral, Luc Taillandier, Laëtitia Imbert and 1 more

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In one paragraph

Article in European journal of nuclear medicine and molecular imaging, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 34 papers, 5 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
34citing papers in PubMed, 5 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

34 citing papers in PubMed, 5 syntheses or guidelines pooled it.

  1. Pooled it
  2. Pooled it
  3. Guideline
  4. Pooled it
  5. Usefulness ofCancer imaging : the official publication of the International Cancer Imaging Society · 2020
    Pooled it
  6. Review
  7. Article
  8. Integrating clinical features withBMC medical imaging · 2025
    Article
  9. Article
  10. Diagnostic accuracy of anti-3-[European journal of nuclear medicine and molecular imaging · 2024
    Article
  11. Review
  12. Review
  13. Article
  14. Article
  15. Review
  16. Article
  17. Review
  18. Journal of nuclear medicine : official publication, Society of Nuclear Medicine · 2022
    Article
  19. Dynamic amino-acid PET in neuro-oncology: a prognostic tool becomes essential.European journal of nuclear medicine and molecular imaging · 2021
    Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors.

Merwan GinetCHRU-Nancy, Department of Nuclear Medicine & Nancyclotep Imaging platform, Université de Lorraine, F-54000, Nancy, France.
Timothée ZaragoriCHRU-Nancy, Department of Nuclear Medicine & Nancyclotep Imaging platform, Université de Lorraine, F-54000, Nancy, France.
Pierre-Yves MarieCHRU-Nancy, Department of Nuclear Medicine & Nancyclotep Imaging platform, Université de Lorraine, F-54000, Nancy, France.
Véronique RochCHRU-Nancy, Department of Nuclear Medicine & Nancyclotep Imaging platform, Université de Lorraine, F-54000, Nancy, France.
Guillaume GauchotteCHRU-Nancy, Department of Pathology, Université de Lorraine, F-54000, Nancy, France.
Fabien RechDepartment of Neurosurgery, CHU-Nancy, F-54000, Nancy, France.
Marie BlonskiDepartment of Neurosurgery, CHU-Nancy, F-54000, Nancy, France.
Zohra LamiralUniversité de Lorraine, INSERM U1116, F-54000, Nancy, France.
Luc TaillandierCentre de Recherche en Automatique de Nancy CRAN, CNRS UMR 7039, Université de Lorraine, F-54000, Nancy, France.
Laëtitia ImbertCHRU-Nancy, Department of Nuclear Medicine & Nancyclotep Imaging platform, Université de Lorraine, F-54000, Nancy, France.
Antoine VergerCHRU-Nancy, Department of Nuclear Medicine & Nancyclotep Imaging platform, Université de Lorraine, F-54000, Nancy, France. a.verger@chru-nancy.fr.ORCID 0000-0003-2194-0328

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

purpose

methodsWe retrospectively included 58 patients having undergone an

resultsThere were 21 IDH mutant without 1p/19q co-deletion (IDH+/1p19q-) gliomas, 16 IDH mutants with 1p/19q co-deletion (IDH+/1p19q+) gliomas, and 21 IDH wildtype (IDH-) gliomas. Dynamic parameters enabled differentiating the gliomas according to these molecular features, whereas static parameters did not. In particular, a longer TTP was the single best independent predictor for identifying (1) IDH mutation status (area under the curve (AUC) of 0.789, global accuracy of 74% for the criterion of a TTP ≥ 5.4 min) and (2) 1p/19q co-deletion status (AUC of 0.679, global accuracy of 69% for the criterion of a TTP ≥ 6.9 min). Moreover, the TTP from IDH- gliomas was significantly shorter than those from both IDH+/1p19q- and IDH+/1p19q+ (p ≤ 0.007).

conclusionPrediction of the molecular features of newly diagnosed gliomas with

Indexed as

Brain NeoplasmsGliomaHumansIsocitrate DehydrogenaseMutationPositron-Emission TomographyRetrospective StudiesIsocitrate Dehydrogenase18F-FDopa PETDiagnosisDynamic analysisGliomaIDH mutationWHO 2016 classification

Identifiers

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Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.