Evidence map›Paper›PMID 31529194›Full record

ArticleInternational journal of colorectal disease2019

Prophylactic negative wound therapy in laparotomy wounds (PROPEL trial): randomized controlled trial.

Noel Edward Donlon, P A Boland, M E Kelly, K Schmidt, F Cooke, P M Neary, K M Barry, J V Reynolds

2 registry-linked trialsAbstract readClinical Trial Protocol
PubMed Publisher
In one paragraph

Article in International journal of colorectal disease, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to 2 registered trials, which are not on this map. Cited by 5 papers, 4 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed, 4 pooled it
2.0field-weighted citation impact, top 14% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT03871023 naunknown statusnot on this map

The Use of Prophylactic Negative Wound Therapy in Emergency and Elective Laparotomy Wounds

TypeinterventionalSponsorSt. James's Hospital, IrelandRan2019 to 2020Enrolled240ConditionsWound Infection, Wounds, Dehisence, CosmesisArmsSmith & Nephew PICO Negative wound pressure versus standard dresing, PREVENA Negative pressure wound versus standard dressing
NCT04472416 nacompletednot on this mapstarted 2021, after this paper: background citation

Impact of Virtual Reality Distraction on Pain and Anxiety for Bedside Abdominal VAC Dressing Change - A Randomized Controlled Clinical Trial (VIRPA)

TypeinterventionalSponsorUniversity of Lausanne HospitalsRan2021 to 2023Enrolled40ConditionsPain, Anxiety, Satisfaction, PatientArmsVRD in addition to standardized analgesic protocol
3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 4 syntheses or guidelines pooled it, 13 citations in OpenAlex.

  1. Pooled it
  2. Pooled it
  3. Pooled it
  4. Pooled it
  5. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 4 institutions in 1 country.

Noel Edward DonlonDepartment of Surgery, St James Hospital, Dublin 8, Ireland. donlonn@tcd.ie.
P A BolandDepartment of Surgery, St James Hospital, Dublin 8, Ireland.ORCID http://orcid.org/0000-0002-5844-7695
M E KellyDepartment of Surgery, St James Hospital, Dublin 8, Ireland.
K SchmidtDepartment of Surgery, Wexford General Hospital, Wexford, Ireland.
F CookeDepartment of Surgery, University Hospital Waterford, Waterford, Ireland.
P M NearyDepartment of Surgery, University Hospital Waterford, Waterford, Ireland.
K M BarryDepartment of Surgery, Mayo University Hospital, Mayo, Ireland.
J V ReynoldsDepartment of Surgery, St James Hospital, Dublin 8, Ireland.
St. James's Hospital · IEUniversity Hospital Waterford · IEMayo General Hospital · IEWexford General Hospital · IE

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundSuperficial surgical site infections are a common post-operative complication. They also place a considerable financial burden on healthcare. The use of prophylactic negative pressure wound therapy has been advocated to reduce wound infection rates. However, there is debate around its routine use. The purpose of this trial is to determine if prophylactic negative pressure wound therapy reduces post-operative wound complications in patients undergoing laparotomy. METHODS/

designThis multi-centre randomised controlled trial will compare standard surgical dressings (control) to two competing negative pressure wound therapy dressings (Prevena™ and PICO™). All patients will be over 18 years, who are undergoing an emergency or elective laparotomy. It is intended to enrol a total of 271 patients for the trial. DISCUSSION: The PROPEL trial is a multi-centre randomised controlled trial of patients undergoing laparotomy. The comparison of standard treatment to two commercially available NPWT will help provide consensus on the routine management of laparotomy wounds.

trial registrationThis study is registered with ClinicalTrials.gov (NCT number NCT03871023).

Indexed as

LaparotomyNegative-Pressure Wound TherapyWounds and InjuriesHumansMulticenter Studies as TopicRandomized Controlled Trials as TopicWound HealingEmergency surgeryNegative pressure wound therapySurgical site infectionWound management

Identifiers

PMID31529194
OpenAlexW2974287331

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.