Evidence map›Paper›PMID 31528842›Full record

ArticleRheumatology advances in practice2019

Tuberculosis in people with rheumatic disease in Finland 1995-2007: a nationwide retrospective register study.

Marjo Vuorela, Nina J Mars, Juha Salonen, Markku J Kauppi

Open access · goldAbstract read
In one paragraph

Article in Rheumatology advances in practice, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
1.5field-weighted citation impact, top 17% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 12 citations in OpenAlex.

  1. Rheumatoid arthritis-associated airway disease: longitudinal pulmonary function behavior.Jornal brasileiro de pneumologia : publicacao oficial da Sociedade Brasileira de Pneumologia e Tisilogia · 2024
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 3 institutions in 1 country.

Marjo VuorelaInternal Medicine Department, Päijät-Häme Central Hospital, Lahti.
Nina J MarsFaculty of Medicine, University of Helsinki.ORCID 0000-0002-7259-5993
Juha SalonenInternal Medicine Department, Vaasa Central Hospital, Vaasa, Finland.
Markku J KauppiInternal Medicine Department, Päijät-Häme Central Hospital, Lahti.
Päijät-Hämeen Keskussairaala · FIUniversity of Helsinki · FIVaasa Central Hospital · FI

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectivesRA and its medication, especially TNF-α inhibitors, increase the risk of clinical tuberculosis (TB) infection. We aimed to investigate the clinical manifestations, incidence and temporal changes in TB occurring concurrently with rheumatic diseases (RDs) between 1995 and 2007.

methodsWe combined the register of the Social Insurance Institution of Finland and the National Infectious Disease Register to find adult patients with reimbursed DMARDs and with a TB notification between 1995 and 2007. After reviewing the medical records, we described their clinical manifestations and medications, explored TB incidence trends using Poisson regression, and compared the incidence of TB with that of the general population.

resultsWe identified 291 patients with both TB and rheumatic disease (RD), 196 of whom had RA. Between 1995 and 2007, the incidence of TB in adult RD decreased from 58.8 to 30.0 per 100 000 (trend

conclusionThe incidence of TB among RD patients was ∼4-fold that of the general population, and it declined between 1995 and 2007. Disseminated TB was present in nearly 20% of patients.

Indexed as

disseminated tuberculosisDMARDslatent tuberculosispulmonary tuberculosisrheumatic diseaserheumatoid arthritistuberculosis incidencetumour necrosis factor inhibitors

Identifiers

PMID31528842
PMCPMC6736076
OpenAlexW2965173221

What OpenQuestion holds

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LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.