Evidence map›Paper›PMID 31528825›Full record

ArticleJournal of the Endocrine Society2019

Cardiometabolic Risk Profile Among Young Adult Females With a History of Premature Adrenarche.

Jani Liimatta, Pauliina Utriainen, Tomi Laitinen, Raimo Voutilainen, Jarmo Jääskeläinen

Open access · goldAbstract read
In one paragraph

Article in Journal of the Endocrine Society, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
16citing papers in PubMed, 2 pooled it
3.2field-weighted citation impact, top 9% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

16 citing papers in PubMed, 2 syntheses or guidelines pooled it, 35 citations in OpenAlex.

  1. Pooled it
  2. Pooled it
  3. Article
  4. Article
  5. Observational
  6. Article
  7. Article
  8. Article
  9. Review
  10. Article
  11. Article
  12. Acanthosis Nigricans: Pointer of Endocrine Entities.Diagnostics (Basel, Switzerland) · 2022
    Review
  13. Non-PCOS Hyperandrogenic Disorders in Adolescents.Seminars in reproductive medicine · 2022
    Article
  14. Normal and Premature Adrenarche.Endocrine reviews · 2021
    Review
  15. Observational
  16. Update on adrenarche.Current opinion in pediatrics · 2020
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 1 institution in 1 country.

Jani LiimattaDepartment of Pediatrics, University of Eastern Finland, Kuopio, Finland.ORCID 0000-0001-6076-1512
Pauliina UtriainenDepartment of Pediatrics, University of Eastern Finland, Kuopio, Finland.
Tomi LaitinenDepartment of Clinical Physiology and Nuclear Medicine, University of Eastern Finland, Kuopio, Finland.
Raimo VoutilainenDepartment of Pediatrics, University of Eastern Finland, Kuopio, Finland.
Jarmo JääskeläinenDepartment of Pediatrics, University of Eastern Finland, Kuopio, Finland.
University of Eastern Finland · FI

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

contextPremature adrenarche (PA) is associated with childhood overweight and hyperinsulinemia; the long-term cardiometabolic outcome is unknown.

objectiveTo study cardiometabolic profile in adult women with previous PA. DESIGN AND

participantsThirty women with PA and 41 control subjects were followed from prepuberty to young adulthood.

main outcome measuresPrevalence of the metabolic syndrome (MetS) and clinical and biochemical cardiovascular risk factors.

resultsThere were no differences in the prevalence of MetS or in any parameters indicating dyslipidemia, hypertension, hepatosteatosis, atherosclerosis, or low-grade inflammation between the study groups. However, prevalence of insulin resistance (IR;

conclusionPA does not seem to be associated with MetS, dyslipidemia, hypertension, atherosclerosis, or low-grade inflammation in young adult women. However, some women with PA may be at an increased risk of unfavorable glucose metabolism, which is associated with increased central adiposity at adult age rather than determined by prepubertal factors.

Indexed as

body compositiondehydroepiandrosterone sulfateinsulin resistancemetabolic syndrome

Identifiers

PMID31528825
PMCPMC6733041
OpenAlexW2962023691

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.