ArticleJournal of current ophthalmology2019
Spectral domain optical coherence tomography findings in Turkish sickle-cell disease and beta thalassemia major patients.
Article in Journal of current ophthalmology, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers.
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Who cites it
13 citing papers in PubMed, 16 citations in OpenAlex.
- Spectral-domain optical coherence tomography characteristics in patients with transfusion-dependent thalassemia.Indian journal of ophthalmology · 2026Article
- Genetic, clinical, and biological risk factors associated with optic nerve thinning in sickle cell disease.Eye (London, England) · 2026Article
- Iron-associated central macular ganglion cell complex thinning and choroidal vascularity index elevation in transfusion-dependent β-thalassemia: potential OCT/OCTA biomarkers.BMC ophthalmology · 2025Article
- Optical coherence tomography findings in beta-thalassemia major: a systematic review and Meta-analysis.International journal of ophthalmology · 2025Article
- Does thalassemia truly cause microvascular changes without us noticing? An optical coherence tomography angiography study of the children with beta-thalassemia.International ophthalmology · 2023Article
- Optical coherence tomography findings in patients with transfusion-dependent β-thalassemia.BMC ophthalmology · 2022Article
- Evaluation of Optical Coherence Tomography Findings and Choroidal Thickness in Beta-Thalassemia Major Patients Using Chelation Therapy.Beyoglu eye journal · 2022Article
- Macular microvascular changes in children with transfusion-dependent beta-thalassemia.Graefe's archive for clinical and experimental ophthalmology = Albrecht von Graefes Archiv fur klinische und experimentelle Ophthalmologie · 2021Observational
- Choroidal Thickness Evaluation in a Transfusion-Dependent Beta-Thalassemia Greek Population.Clinical ophthalmology (Auckland, N.Z.) · 2020Article
- Ocular Biometric Findings in Thalassemia Major: A Systematic Review and Meta-Analysis.Journal of current ophthalmologyReview
- Chronic Effects of e-Cigarette Aerosol Inhalation on Macular Perfusion Assessed Using OCT Angiography.Journal of vitreoretinal diseasesArticle
- Article
- Ocular biometry, anterior chamber morphometry, and their relationship with serum ferritin levels in children with beta thalassemia major.Therapeutic advances in ophthalmologyArticle
Corrections and comments
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Authors and funding
3 authors at 3 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
purposeTo assess probable structural changes using spectral domain optical coherence tomography (SD-OCT) on sickle-cell disease (SCD) and beta thalassemia major (B-TM) patients, without any retinal abnormalities.
methodsThis cross-sectional study included 32 B-TM, 34 SCD patients, and 44 healthy controls. One of the eyes of all participants was evaluated for SD-OCT and choroidal thickness, retinal nerve fiber layer (RNFL) thickness, central macular thickness (CMT), ganglion cell complex (GCC).
resultsAge, gender, and intraocular pressure (IOP) were not statistically different between the three groups. Hemoglobin (Hgb), hematocrite (Htc), and ferritin levels were not statistically different between the SCD and B-TM groups. Choroidal thickness at the subfoveal region was statistically higher in the control group (353.79 ± 71.93) than in the B-TM (317.41 ± 53.44) and SCD (283.21 ± 63.27) groups. In addition, it was statistically higher in the B-TM group than the SCD group (
conclusionIn both diseases, we can show early structural changes even if proliferative or non-proliferative retinopathy or other ocular manifestations were not developed yet.
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