Evidence map›Paper›PMID 31528362›Full record

ArticleEnvironmental epigenetics2019

Cadmium exposure and

John S House, Jonathan Hall, Sarah S Park, Antonio Planchart, Eric Money, Rachel L Maguire, Zhiqing Huang, Carolyn J Mattingly, David Skaar, Jung Ying Tzeng and 5 more

Open access · goldAbstract read
In one paragraph

Article in Environmental epigenetics, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers.

0numbers the graph read from it
0cells of the map it votes in
13citing papers in PubMed
0.7field-weighted citation impact, top 31% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

13 citing papers in PubMed, 16 citations in OpenAlex.

  1. Review
  2. Review
  3. Mechanisms of Heavy Metal Cadmium (Cd)-Induced Malignancy.Biological trace element research · 2025
    Review
  4. Article
  5. Review
  6. Imprinting and Reproductive Health: A Toxicological Perspective.International journal of molecular sciences · 2023
    Review
  7. Review
  8. The imprinted gene Zac1 regulates steatosis in developmental cadmium-induced nonalcoholic fatty liver disease.Toxicological sciences : an official journal of the Society of Toxicology · 2023
    Article
  9. Article
  10. Review
  11. DNA methylation and gene expression alterations in zebrafish embryos exposed to cadmium.Environmental science and pollution research international · 2021
    Article
  12. Observational
  13. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

15 authors at 3 institutions in 1 country.

John S HouseCenter for Human Health and the Environment, North Carolina State University, Raleigh, NC, USA.ORCID 0000-0002-8447-7871
Jonathan HallCenter for Human Health and the Environment, North Carolina State University, Raleigh, NC, USA.
Sarah S ParkCenter for Human Health and the Environment, North Carolina State University, Raleigh, NC, USA.
Antonio PlanchartCenter for Human Health and the Environment, North Carolina State University, Raleigh, NC, USA.
Eric MoneyCenter for Geospatial Analytics, North Carolina State University, Raleigh, NC, USA.
Rachel L MaguireCenter for Human Health and the Environment, North Carolina State University, Raleigh, NC, USA.
Zhiqing HuangDepartment of Obstetrics and Gynecology, Duke University School of Medicine, Durham, NC, USA.
Carolyn J MattinglyCenter for Human Health and the Environment, North Carolina State University, Raleigh, NC, USA.
David SkaarCenter for Human Health and the Environment, North Carolina State University, Raleigh, NC, USA.
Jung Ying TzengCenter for Human Health and the Environment, North Carolina State University, Raleigh, NC, USA.
Thomas H DarrahDivision of Climate, Water, and Environment, School of Earth Sciences, The Ohio State University, Columbus, OH, USA.
Avner VengoshNicholas School of the Environment, Duke University, Durham, NC, USA.
Susan K MurphyDepartment of Obstetrics and Gynecology, Duke University School of Medicine, Durham, NC, USA.
Randy L JirtleCenter for Human Health and the Environment, North Carolina State University, Raleigh, NC, USA.
Cathrine HoyoCenter for Human Health and the Environment, North Carolina State University, Raleigh, NC, USA.
North Carolina State University · USDuke University · USThe Ohio State University · US

Funding

Zebrafish as a Detector of Organophosphate ExposureP42ES010356 · NIEHS · DUKE UNIVERSITY · PI AMY H HERRING · 2000 to 2026
$56.2M
Social adversities, epigenetics, and the obesity epidemicR01MD011746 · NIMHD · NORTH CAROLINA STATE UNIVERSITY RALEIGH · PI HOYO, CATHRINE · 2017 to 2021
$4.4M
Follow-up and Maintenance of the Newborn Epigenetics STudy (NEST) CohortR24ES028531 · NIEHS · NORTH CAROLINA STATE UNIVERSITY RALEIGH · PI HOYO, CATHRINE, MURPHY, SUSAN KAY · 2018 to 2022
$1.9M
NIEHS NIH HHS P42 ES010356NIEHS NIH HHS R24 ES028531NIMHD NIH HHS R01 MD011746
6 · The paper itself

Abstract

Cadmium (Cd) is a ubiquitous environmental pollutant associated with a wide range of health outcomes including cancer. However, obscure exposure sources often hinder prevention efforts. Further, although epigenetic mechanisms are suspected to link these associations, gene sequence regions targeted by Cd are unclear. Aberrant methylation of a differentially methylated region (DMR) on the

Indexed as

cadmiumCpG methylationimprinted genesmaternal exposuresoffspring epigeneticsracial epigenetic outcome differences

Identifiers

PMID31528362
PMCPMC6736358
OpenAlexW2971118381

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.