Evidence map›Paper›PMID 31528284›Full record

ArticleJournal of community hospital internal medicine perspectives2019

Ecstasy induced acute systolic heart failure and Non-Ischemic Cardiomyopathy in a young female: a rare case report and literature review.

Paritosh Kafle, Binav Shrestha, Amrendra Mandal, Dikshya Sharma, Manjul Bhandari, Birendra Amgai, Mazin Khalid, Jasdeep S Sidhu, Isaac Solaimanzadeh, Vijay Gayam and 2 more

Open access · goldAbstract readCase Reports
In one paragraph

Article in Journal of community hospital internal medicine perspectives, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
0.4field-weighted citation impact, top 43% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 7 citations in OpenAlex.

  1. Article
  2. Rare but relevant: MDMA and hyponatraemia.Addiction (Abingdon, England) · 2026
    Review
  3. Article
  4. Article
  5. Stimulant Drugs of Abuse and Cardiac Arrhythmias.Circulation. Arrhythmia and electrophysiology · 2022
    Review
  6. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors at 2 institutions in 1 country.

Paritosh KafleDepartment of Internal Medicine, Interfaith Medical Center, Brooklyn, NY, USA.ORCID 0000-0002-4345-1392
Binav ShresthaDepartment of Internal Medicine, Interfaith Medical Center, Brooklyn, NY, USA.ORCID 0000-0002-6839-4726
Amrendra MandalDepartment of Internal Medicine, Interfaith Medical Center, Brooklyn, NY, USA.ORCID 0000-0002-5873-5443
Dikshya SharmaDepartment of Internal Medicine, Maimonides Medical Center, Brooklyn, NY, USA.
Manjul BhandariDepartment of Internal Medicine, Interfaith Medical Center, Brooklyn, NY, USA.
Birendra AmgaiDepartment of Internal Medicine, Interfaith Medical Center, Brooklyn, NY, USA.
Mazin KhalidDepartment of Internal Medicine, Interfaith Medical Center, Brooklyn, NY, USA.ORCID 0000-0003-4868-4299
Jasdeep S SidhuDepartment of Internal Medicine, Interfaith Medical Center, Brooklyn, NY, USA.ORCID 0000-0003-2790-2437
Isaac SolaimanzadehDepartment of Internal Medicine, Interfaith Medical Center, Brooklyn, NY, USA.
Vijay GayamDepartment of Internal Medicine, Interfaith Medical Center, Brooklyn, NY, USA.ORCID 0000-0001-5194-9134
Rahul SuranaDepartment of Internal Medicine, Interfaith Medical Center, Brooklyn, NY, USA.
Alix DufresneDepartment of Cardiology, Interfaith Medical Center, Brooklyn, NY, USA.
Interfaith Medical Center · USMaimonides Medical Center · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Ecstasy or 3,4-methylenedioxymethamphetamine (MDMA) is an illicit recreational drug. Effects include euphoria, increased sensory awareness, and central stimulation. Although various arrhythmias, as well as dilated cardiomyopathy, have been previously noted to occur with chronic use, cardiac toxicities are seldom reported in an acute setting. Herein, we present a 28-year-old female patient with no prior medical condition that presented to the Emergency Department with chest pain following intake of MDMA. Electrocardiographic findings, as well as laboratories, were suggestive of possible Acute Non-ST elevation myocardial infarction. Upon admission, cardiac catheterization revealed patent coronary arteries. Stark regional wall motion abnormalities were observed along with reduced ejection fraction. Acute systolic heart failure was treated with standard medical management. Subsequent reassessment of ventricular function with Echocardiography revealed marked improvement. This article describes a case of MDMA induced heart failure, including details of evaluation, management, and monitoring of patient progress. It brings further attention to potential acute harmful effects of MDMA on cardiac function and viability.

Indexed as

Ecstasyheart failurenon-ischemic cardiomyopathynon-ST elevation MIsystolic dysfunction

Identifiers

PMID31528284
PMCPMC6735291
OpenAlexW2971942550

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.