Evidence map›Paper›PMID 31528251›Full record

ArticleJournal of dental sciences2019

Dysphagia and risk of aspiration pneumonia: A nonrandomized, pair-matched cohort study.

Wen-Liang Lo, Hsin-Bang Leu, Mu-Chen Yang, Ding-Han Wang, Ming-Lun Hsu

Open access · goldAbstract read
In one paragraph

Article in Journal of dental sciences, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 18 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
18citing papers in PubMed, 1 pooled it
5.7field-weighted citation impact, top 5% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

18 citing papers in PubMed, 1 synthesis or guideline pooled it, 34 citations in OpenAlex.

  1. Pooled it
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  12. Clinical Practice Guidelines for Oropharyngeal Dysphagia.Annals of rehabilitation medicine · 2023
    Article
  13. Article
  14. Article
  15. Article
  16. Risk Factors for Aspiration Pneumonia After Receiving Liquid-Thickening Recommendations.Otolaryngology--head and neck surgery : official journal of American Academy of Otolaryngology-Head and Neck Surgery · 2022
    Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 4 institutions in 1 country.

Wen-Liang LoDepartment of Dentistry, School of Dentistry, National Yang-Ming University, Taipei, Taiwan.
Hsin-Bang LeuDivision of Cardiology, Department of Medicine, Taipei Veterans General Hospital, Taipei, Taiwan.
Mu-Chen YangDepartment of Dentistry, School of Dentistry, National Yang-Ming University, Taipei, Taiwan.
Ding-Han WangDepartment of Dentistry, School of Dentistry, National Yang-Ming University, Taipei, Taiwan.
Ming-Lun HsuDepartment of Dentistry, School of Dentistry, National Yang-Ming University, Taipei, Taiwan.
National Taipei University · TWNational Yang Ming Chiao Tung University · TWNational Yang Ming Chiao Tung University · TWTaipei Veterans General Hospital · TW

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

background/purposeDysphagia was associated with increased prevalence of aspiration pneumonia (AP) in studies that were criticized for either their small sample size or lack of prospective design. Using a considerably larger nationwide, population-based database and a long-term prospective cohort design, our study aimed to explore the relationship between dysphagia and the subsequent development of AP. MATERIALS AND

methodsFrom 2000 to 2009, we gathered a study cohort consisting of 6979 newly diagnosed cases of dysphagia from Taiwan's National Health Insurance Research Database. For the control group, another 20,937 individuals without dysphagia were matched for age, sex, and comorbidity. The two cohorts were followed-up to observe the occurrence of AP and correlated mortality.

resultsDuring an average of 3.88 ± 2.73 years of follow-up, we observed 315 cases of new AP [non-dysphagia (193, 0.92%) vs. dysphagia (122, 1.75%), p < 0.0001], and the incidence of AP was significant in the dysphagia group. After adjusting for age, sex, and comorbidity, dysphagia-related AP [hazard ratio (HR) 2.499; 95% confidence interval (CI), 2.089-2.99; p < 0.0001], dysphagia related mortality [HR 3.229; 95% CI, 3.052-3.417; p < 0.0001], and many other systemic diseases were independently associated with a diagnosis of AP.

conclusionDysphagia was highly associated with an increased risk of AP according to data derived from a large nationwide cohort database. Nonetheless, larger prospective studies or meta-analyses are recommended to confirm our findings.

Indexed as

Aspiration pneumoniaDysphagiaMortality

Identifiers

PMID31528251
PMCPMC6739300
OpenAlexW2924918500

What OpenQuestion holds

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LicenceCC BY-NC-ND
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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.