ArticleAnnals of general psychiatry2019
White matter abnormalities of corpus callosum in patients with bipolar disorder and suicidal ideation.
Article in Annals of general psychiatry, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers, 1 of them a synthesis that pooled it.
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Who cites it
16 citing papers in PubMed, 1 synthesis or guideline pooled it, 31 citations in OpenAlex.
- Structural connectivity abnormalities in suicidal thoughts and behaviours: a meta-analysis.Translational psychiatry · 2025Pooled it
- Brain White Matter Microstructure in Middle and Older Aged Adults With Bipolar Disorder: A 2-Site Study.The American journal of geriatric psychiatry : official journal of the American Association for Geriatric Psychiatry · 2026Article
- White Matter Regional Volumes in Relation to Menstrual Cycle Phase and Premenstrual Dysphoric Disorder.Biological psychiatry global open science · 2025Article
- Transdiagnostic alterations in white matter microstructure associated with suicidal thoughts and behaviours in the ENIGMA Suicidal Thoughts and Behaviours consortium.Translational psychiatry · 2025Article
- An observational study on gray matter volume and white matter integrity in suicide attempters with bipolar I disorder.Indian journal of psychiatry · 2025Article
- The shape of the corpus callosum is different in bipolar disorder.Acta neuropsychiatrica · 2024Article
- A graph theory neuroimaging approach to distinguish the depression of bipolar disorder from major depressive disorder in adolescents and young adults.Journal of affective disorders · 2022Article
- Diffusion tensor imaging studies on subjects with suicidal thoughts and behaviors: A descriptive literature review.Brain and behavior · 2022Review
- Insights into myelin dysfunction in schizophrenia and bipolar disorder.World journal of psychiatry · 2022Review
- Neuroimaging Studies of Brain Structure in Older Adults with Bipolar Disorder: A Review.Journal of psychiatry and brain science · 2022Article
- Exploratory study on neurochemical effects of low-intensity pulsed ultrasound in brains of mice.Medical & biological engineering & computing · 2021Article
- Mapping Brain Microstructure and Network Alterations in Depressive Patients with Suicide Attempts Using Generalized Q-Sampling MRI.Journal of personalized medicine · 2021Article
- The Correlation of Reduced Fractional Anisotropy in the Cingulum With Suicide Risk in Bipolar Disorder.Frontiers in psychiatry · 2021Article
- Assessment of Disrupted Brain Structural Connectome in Depressive Patients With Suicidal Ideation Using Generalized Q-Sampling MRI.Frontiers in human neuroscience · 2021Article
- White Matter Correlates of Suicidality in Adults With Bipolar Disorder Who Have Been Prospectively Characterized Since Childhood.Biological psychiatry. Cognitive neuroscience and neuroimaging · 2021Article
- White matter microstructure and volume correlates of premenstrual dysphoric disorder.Journal of psychiatry & neuroscience : JPNArticle
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
6 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
objectiveAlthough many studies have shown that the corpus callosum (CC) may play an important role in bipolar disorder (BD) and suicide, the pathophysiological mechanism of BD underlying suicidal behavior is still unclear. This study aimed to explore the relationship between the CC, and BD and suicidal ideation using diffusion tensor imaging (DTI).
methodA total of 203 participants (47 BD patients with suicidal ideation, 59 with BD without suicidal ideation, and 97 healthy controls [HC]) underwent DTI scanning at a single site. We examined the white matter integrity of the CC in the three groups.
resultsA comparison among groups showed that BD patients with suicidal ideation had significant lower fractional anisotropy (FA) values than those of BD without suicidal ideation and HCs in the body and genu of the CC, and FA values of BD without suicidal ideation were significantly lower than those of HCs. However, in the splenium of corpus callosum, no difference was found between BD without suicidal ideation and HCs.
conclusionsOur findings add to the evidence suggesting that the CC plays a key role in BD with suicidal ideation, especially with respect to the role of the genu and body of the CC subserving emotion regulation.
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.