ArticleFrontiers in zoology2019
Gene expression vs. sequence divergence: comparative transcriptome sequencing among natural
Article in Frontiers in zoology, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers.
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13 citing papers in PubMed, 19 citations in OpenAlex.
- Gene Ontology-Based Comparative Transcriptomics Provides Evidence of Genetic Adaptations in theAnimals : an open access journal from MDPI · 2026Article
- Different Species of Bats: Genomics, Transcriptome, and Immune Repertoire.Current issues in molecular biology · 2025Review
- Selection Over Small and Large Spatial Scales in the Face of High Gene Flow.Molecular ecology · 2025Article
- The roles of different gene expression regulators in acoustic variation in the intermediate horseshoe bat revealed by long-read and short-read RNA sequencing data.Current zoology · 2024Article
- Sex Differences in Cochlear Transcriptomes in Horseshoe Bats.Animals : an open access journal from MDPI · 2024Article
- Full-Length Transcriptome of the Great Himalayan Leaf-Nosed Bats (International journal of molecular sciences · 2023Article
- Diversifying selection and climatic effects on major histocompatibility complex class II gene diversity in the greater horseshoe bat.Evolutionary applications · 2023Article
- Article
- Extensive Adaptive Variation in Gene Expression within and between Closely Related Horseshoe Bats (Chiroptera,Animals : an open access journal from MDPI · 2022Article
- Characterization of microRNA and gene expression in the cochlea of an echolocating bat (Ecology and evolution · 2022Article
- Assembly-free rapid differential gene expression analysis in non-model organisms using DNA-protein alignment.BMC genomics · 2022Article
- Transcriptome sequencing of cochleae from constant-frequency and frequency-modulated echolocating bats.Scientific data · 2020Article
- Echolocation call frequency variation in horseshoe bats: molecular basis revealed by comparative transcriptomics.Proceedings. Biological sciences · 2020Article
Corrections and comments
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Authors and funding
9 authors at 3 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundAlthough the sensory drive hypothesis can explain the geographic variation in echolocation frequencies of some bat species, the molecular mechanisms underlying this phenomenon are still unclear. The three lineages of greater horseshoe bat (
resultsA total of 8190 differentially expressed genes (DEGs) were identified. We identified five modules from all DEGs that were significantly related to RF or forearm length (FL). DEGs in the RF-related modules were significantly enriched in the gene categories involved in neural activity, learning, and response to sound. DEGs in the FL-related modules were significantly enriched in the pathways related to muscle and actin functions. Using 21,945 single nucleotide polymorphisms, we identified 18 candidate unigenes associated with hearing, five of which were differentially expressed among the three populations. Additionally, the gene
conclusionsThe variability of gene expression and sequence divergence at the molecular level might provide evidence that can help elucidate the genetic basis of geographic variation in echolocation signals of greater horseshoe bats.
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