Evidence map›Paper›PMID 31528090›Full record

ReviewWorld journal of gastroenterology2019

Locoregional treatments for hepatocellular carcinoma: Current evidence and future directions.

Riccardo Inchingolo, Alessandro Posa, Martin Mariappan, Stavros Spiliopoulos

Open access · hybridAbstract readReview
PubMed Full text at PMC Publisher
In one paragraph

Review in World journal of gastroenterology, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 63 papers, 4 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
63citing papers in PubMed, 4 pooled it
12.3field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

63 citing papers in PubMed, 4 syntheses or guidelines pooled it, 134 citations in OpenAlex.

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3 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 3 institutions in 2 countries.

Riccardo InchingoloDivision of Interventional Radiology, Department of Radiology, Madonna delle Grazie Hospital, Matera 75100, Italy.
Alessandro PosaDepartment of Radiology, IRCSS Fatebenefratelli Hospital, Roma 00186, Italy.
Martin MariappanInterventional Radiology Department, Aberdeen Royal Infirmary Hospital, Aberdeen AB25 2ZN, United Kingdom.
Stavros Spiliopoulos2nd Radiology Department, School of Medicine; National and Kapodistrian University of Athens, Chaidari Athens 12461, Greece.
Aberdeen Royal Infirmary · GBFatebenefratelli Hospital · ITOspedale Madonna Delle Grazie · IT

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Liver cancers are the second most frequent cause of global cancer-related mortality of which 90% are attributable to hepatocellular carcinoma (HCC). Despite the advent of screening programmes for patients with known risk factors, a substantial number of patients are ineligible for curative surgery at presentation with limited outcomes achievable with systemic chemotherapy/external radiotherapy. This has led to the advent of numerous minimally invasive options including but not limited to trans-arterial chemoembolization, radiofrequency/microwave ablation and more recently selective internal radiation therapy many of which are often the first-line treatment for select stages of HCC or serve as a conduit to liver transplant. The authors aim to provide a comprehensive overview of these various image guided minimally invasive therapies with a brief focus on the technical aspects accompanied by a critical analysis of the literature to assess the most up-to-date evidence from comparative systematic reviews and meta-analyses finishing with an assessment of novel combination regimens and future directions of travel.

Indexed as

Ablation TechniquesAntineoplastic AgentsCarcinoma, HepatocellularChemoembolization, TherapeuticCombined Modality TherapyGastroenterologyHumansLiver NeoplasmsMedical OncologyMeta-Analysis as TopicMinimally Invasive Surgical ProceduresNeoplasm StagingProgression-Free SurvivalRadiography, InterventionalSystematic Reviews as TopicAntineoplastic AgentsAblationCirrhosisHepatocellular carcinomaInterventional oncologyLiverSelective internal radiation therapyTrans-arterial chemo embolization

Identifiers

PMID31528090
PMCPMC6718039
OpenAlexW2970269645

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.