Evidence map›Paper›PMID 31527862›Full record

ReviewNature reviews. Gastroenterology & hepatology2019

Diagnosis and management of pancreatic cystic neoplasms: current evidence and guidelines.

Nadine C M van Huijgevoort, Marco Del Chiaro, Christopher L Wolfgang, Jeanin E van Hooft, Marc G Besselink

3 registry-linked trialsAbstract readReview
PubMed Publisher
In one paragraph

Review in Nature reviews. Gastroenterology & hepatology, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to 3 registered trials, which are not on this map. Cited by 125 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
125citing papers in PubMed, 2 pooled it
9.7field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT04389892 nacompletednot on this map

Usefulness of Contrast-enhanced Harmonic Endoscopic Ultrasound (CH-EUS) for the Differentiation of the Pancreatic Cysts and for Guiding Endoscopic Ultrasound Guided Fine Needle Aspiration (EUS-FNA) From Murale Nodules.

TypeinterventionalSponsorIuliu Hatieganu University of Medicine and PharmacyRan2018 to 2020Enrolled58ConditionsPancreatic CystArmsContrast enhanced harmonic endoscopic ultrasound
NCT05568433 completednot on this map

New Biomarkers in the Intracystic Liquid of Cystic Pancreatic Lesions

TypeobservationalSponsorIuliu Hatieganu University of Medicine and PharmacyRan2018 to 2020Enrolled63ConditionsPancreatic CystArmsEndoscopic ultrasound fine needle aspiration (EUS-FNA)
NCT06024343 nacompletednot on this map

Long-term Outcome in Minimally Invasive Pancreatic Enucleation With Main Pancreatic Duct Exposure, Repair or Reconstruction: A Prospective Cohort Study

TypeinterventionalSponsorFudan UniversityRan2019 to 2024Enrolled230ConditionsPancreatic Tumor, Benign, Pancreatic Neuroendocrine Tumor, Solid Pseudopapillary Tumor of the PancreasArmsMPD Exposure, Repair or Reconstruction
3 · Its place in the literature

Who cites it

125 citing papers in PubMed, 2 syntheses or guidelines pooled it, 261 citations in OpenAlex.

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  11. Cystic neoplasms of pancreas.Indian journal of gastroenterology : official journal of the Indian Society of Gastroenterology · 2026
    Review
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65 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 4 institutions in 2 countries.

Nadine C M van HuijgevoortDepartment of Gastroenterology and Hepatology, Amsterdam Gastroenterology and Metabolism, Amsterdam UMC, University of Amsterdam, Amsterdam, Netherlands.ORCID http://orcid.org/0000-0002-8651-1164
Marco Del ChiaroDepartment of Surgery, University of Colorado Anschutz Medical Campus, Aurora, Colorado, USA.
Christopher L WolfgangDepartment of Surgery, The Sol Goldman Pancreatic Cancer Research Center, The Johns Hopkins University School of Medicine, Baltimore, MD, USA.
Jeanin E van HooftDepartment of Gastroenterology and Hepatology, Amsterdam Gastroenterology and Metabolism, Amsterdam UMC, University of Amsterdam, Amsterdam, Netherlands.
Marc G BesselinkDepartment of Surgery, Cancer Center Amsterdam, Amsterdam UMC, University of Amsterdam, Amsterdam, Netherlands. m.g.besselink@amsterdamumc.nl.ORCID http://orcid.org/0000-0003-2650-9350
Amsterdam University Medical Centers · NLAmsterdam Neuroscience · NLJohns Hopkins University · USUniversity of Colorado Anschutz Medical Campus · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Pancreatic cystic neoplasms (PCN) are a heterogeneous group of pancreatic cysts that include intraductal papillary mucinous neoplasms, mucinous cystic neoplasms, serous cystic neoplasms and other rare cystic lesions, all with different biological behaviours and variable risk of progression to malignancy. As more pancreatic cysts are incidentally discovered on routine cross-sectional imaging, optimal surveillance for patients with PCN is becoming an increasingly common clinical problem, highlighting the need to balance cancer prevention with the risk of (surgical) overtreatment. This Review summarizes the latest developments in the diagnosis and management of PCN, including the quality of available evidence. Also discussed are the most important differences between the PCN guidelines from the American Gastroenterological Association, the International Association of Pancreatology and the European Study Group on Cystic Tumours of the Pancreas, including diagnostic and follow-up strategies and indications for surgery. Finally, new developments in the management of patients with PCN are addressed.

Indexed as

HumansPancreasPancreatic CystPancreatic Neoplasms

Identifiers

PMID31527862
OpenAlexW2973730192

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.