Evidence map›Paper›PMID 31527829›Full record

ArticleLaboratory investigation; a journal of technical methods and pathology2020

Prostaglandin E2 receptor EP1 (PGE2/EP1) deletion promotes glomerular podocyte and endothelial cell injury in hypertensive TTRhRen mice.

Rania Nasrallah, Joseph Zimpelmann, Susan J Robertson, Jamie Ghossein, Jean-Francois Thibodeau, C R J Kennedy, Alex Gutsol, Fengxia Xiao, Dylan Burger, Kevin D Burns and 1 more

Open access · bronzeAbstract read
PubMed Publisher
In one paragraph

Article in Laboratory investigation; a journal of technical methods and pathology, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
0.9field-weighted citation impact, top 28% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 12 citations in OpenAlex.

  1. Article
  2. Bioactive lipids in hypertension.Advances in pharmacology (San Diego, Calif.) · 2023
    Article
  3. Review
  4. EPActa physiologica (Oxford, England) · 2022
    Article
  5. Review
  6. Article
  7. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors at 1 institution in 1 country.

Rania NasrallahDepartment of Cellular and Molecular Medicine, Faculty of Medicine, Kidney Research Centre, University of Ottawa, 451 Smyth Road, Room 2514, Ottawa, ON, Canada.
Joseph ZimpelmannDepartment of Cellular and Molecular Medicine, Faculty of Medicine, Kidney Research Centre, University of Ottawa, 451 Smyth Road, Room 2514, Ottawa, ON, Canada.
Susan J RobertsonDepartment of Pathology and Laboratory Medicine, Ottawa, ON, Canada.
Jamie GhosseinDepartment of Cellular and Molecular Medicine, Faculty of Medicine, Kidney Research Centre, University of Ottawa, 451 Smyth Road, Room 2514, Ottawa, ON, Canada.
Jean-Francois ThibodeauPrometic Biosciences Inc., Kidney Research Centre, Laval, QC, Canada.
C R J KennedyDepartment of Cellular and Molecular Medicine, Faculty of Medicine, Kidney Research Centre, University of Ottawa, 451 Smyth Road, Room 2514, Ottawa, ON, Canada.ORCID http://orcid.org/0000-0001-5241-860X
Alex GutsolOttawa Hospital Research Institute, Kidney Research Centre, University of Ottawa, Ottawa, ON, Canada.
Fengxia XiaoOttawa Hospital Research Institute, Kidney Research Centre, University of Ottawa, Ottawa, ON, Canada.
Dylan BurgerOttawa Hospital Research Institute, Kidney Research Centre, University of Ottawa, Ottawa, ON, Canada.ORCID http://orcid.org/0000-0003-3951-2911
Kevin D BurnsDepartment of Cellular and Molecular Medicine, Faculty of Medicine, Kidney Research Centre, University of Ottawa, 451 Smyth Road, Room 2514, Ottawa, ON, Canada.
Richard L HébertDepartment of Cellular and Molecular Medicine, Faculty of Medicine, Kidney Research Centre, University of Ottawa, 451 Smyth Road, Room 2514, Ottawa, ON, Canada. rlhebert@uottawa.ca.
University of Ottawa · CA

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Prostaglandin E2 receptor EP1 (PGE

Indexed as

Hypertension, RenalPodocytesReceptors, Prostaglandin E, EP1 SubtypeAnimalsDisease Models, AnimalEndothelial CellsGene DeletionGlomerular Filtration RateKidney GlomerulusMaleMiceMice, TransgenicReceptors, Prostaglandin E, EP1 Subtype

Identifiers

PMID31527829
OpenAlexW2974513539

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.