ReviewNature reviews. Nephrology2020
Measured and estimated glomerular filtration rate: current status and future directions.
Review in Nature reviews. Nephrology, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 160 papers, 3 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
160 citing papers in PubMed, 3 syntheses or guidelines pooled it.
- A meta-analysis of GFR slope as a surrogate endpoint for kidney failure.Nature medicine · 2023Pooled it
- Genetic loci and prioritization of genes for kidney function decline derived from a meta-analysis of 62 longitudinal genome-wide association studies.Kidney international · 2022Pooled it
- Adverse Effects of fine particulate matter on human kidney functioning: a systematic review.Environmental health : a global access science source · 2022Pooled it
- Multi-Parametric Magnetic Resonance Imaging to Assess Empagliflozin Effect on the Kidneys in People With Type 2 Diabetes Mellitus: A Pilot Clinical Trial.Diabetes, obesity & metabolism · 2026Trial
- Separate and combined effects of semaglutide and empagliflozin on kidney oxygenation and perfusion in people with type 2 diabetes: a randomised trial.Diabetologia · 2023Trial
- Trial
- CMolecules (Basel, Switzerland) · 2026Article
- Comparison of eGFR equations for estimating kidney function in Chinese children.Pediatric research · 2026Article
- Brain-kidney crosstalk in subarachnoid hemorrhage patients.Journal of critical care medicine (Universitatea de Medicina si Farmacie din Targu-Mures) · 2026Article
- Diagnostic Accuracy of Eight Estimated Glomerular Filtration Rate Equations for Assessing Kidney Function in Korean Pediatric Patients.Annals of laboratory medicine · 2026Article
- Renal Dose Adjustment in European Primary Care: Clinical Nuances and Practical Challenges.Journal of clinical medicine · 2026Article
- A combined eGFR-CD4 index and mortality risk among people with HIV: a retrospective cohort study in Taizhou city, Zhejiang province, China.AIDS research and therapy · 2026Article
- Serum creatinine to cystatin C ratio and risk of incident digestive diseases in middle-aged and older adults: a prospective national cohort study.Scientific reports · 2026Article
- Renal Functional Reserve and Its Association with eGFR Trajectories and Blood Pressure Patterns in Hypertensives with Preserved Renal Function.High blood pressure & cardiovascular prevention : the official journal of the Italian Society of Hypertension · 2026Article
- Direct Measurement of GFR: Who, When, and How?: A Practical Approach Emphasizing Iohexol Plasma Clearance.Journal of the American Society of Nephrology : JASN · 2026Review
- Impact of Different Glomerular Filtration Rate Equations on Metformin Eligibility in Patients with Diabetes Mellitus and Chronic Kidney Disease.Journal of clinical medicine · 2026Article
- Cystatin C-based eGFR better predicts renal vancomycin clearance than creatinine-based eGFR in patients with allogeneic stem cell transplantation.Clinical pharmacology and therapeutics · 2026Article
- Commentary on ACE‑Is/ARBs in patients with cardio‑renal disease.Internal and emergency medicine · 2026Article
- Large-Scale Proteomic Profiling of Incident Heart Failure and Its Subtypes in Older Adults.Circulation. Genomic and precision medicine · 2026Article
- Impact of Computed Tomography-Derived Body Composition Analysis on the Performance of GFR Estimating Equations in Patients with Cancer.Clinical journal of the American Society of Nephrology : CJASN · 2026Article
100 more citing papers are in PubMed but not listed here.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
5 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Evaluation of glomerular filtration rate (GFR) is central to the assessment of kidney function in medical practice, research and public health. Measured GFR (mGFR) remains the reference standard, but the past 20 years have seen major advances in estimated GFR (eGFR). Both eGFR and mGFR are associated with error compared with true GFR. eGFR is now recommended by clinical practice guidelines, regulatory agencies and public health agencies for the initial evaluation of GFR, with measured GFR (mGFR) typically considered an important confirmatory test, depending on how accurate the assessment of GFR needs to be for application to the clinical, research or public health setting. Our approach is to use initial and confirmatory tests as needed to develop a final assessment of true GFR. We suggest that GFR evaluation might be improved by more complete implementation of current recommendations and by further research to improve the accuracy of mGFR and eGFR.
Indexed as
Identifiers
31527790What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.