Evidence map›Paper›PMID 31527773›Full record

ArticleScientific reports2019

Improving the Function and Engraftment of Transplanted Pancreatic Islets Using Pulsed Focused Ultrasound Therapy.

Mehdi Razavi, Fengyang Zheng, Arsenii Telichko, Jing Wang, Gang Ren, Jeremy Dahl, Avnesh S Thakor

Open access · goldAbstract read
In one paragraph

Article in Scientific reports, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed
1.8field-weighted citation impact, top 15% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed, 13 citations in OpenAlex.

  1. Article
  2. Article
  3. Analyzing Gene Expression After Administration of Low-Intensity Therapeutic Ultrasound in Human Islet Cells.Journal of ultrasound in medicine : official journal of the American Institute of Ultrasound in Medicine · 2024
    Article
  4. Review
  5. Article
  6. Article
  7. Cytosolic CaTheranostics · 2021
    Article
  8. Article
  9. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 3 institutions in 2 countries.

Mehdi RazaviInterventional Regenerative Medicine and Imaging Laboratory, Stanford University School of Medicine, Department of Radiology, Palo Alto, California, 94304, USA.
Fengyang ZhengInterventional Regenerative Medicine and Imaging Laboratory, Stanford University School of Medicine, Department of Radiology, Palo Alto, California, 94304, USA.
Arsenii TelichkoJeremy Dahl Ultrasound Laboratory, Stanford University School of Medicine, Department of Radiology, Palo Alto, California, 94304, USA.
Jing WangInterventional Regenerative Medicine and Imaging Laboratory, Stanford University School of Medicine, Department of Radiology, Palo Alto, California, 94304, USA.
Gang RenInterventional Regenerative Medicine and Imaging Laboratory, Stanford University School of Medicine, Department of Radiology, Palo Alto, California, 94304, USA.
Jeremy DahlJeremy Dahl Ultrasound Laboratory, Stanford University School of Medicine, Department of Radiology, Palo Alto, California, 94304, USA.ORCID http://orcid.org/0000-0001-9877-452X
Avnesh S ThakorInterventional Regenerative Medicine and Imaging Laboratory, Stanford University School of Medicine, Department of Radiology, Palo Alto, California, 94304, USA. asthakor@stanford.edu.
Stanford University · USShanghai Medical College of Fudan University · CNStanford Medicine · US

Funding

Stanford Islet Research CoreP30DK116074 · NIDDK · STANFORD UNIVERSITY · PI Seung K Kim · 2017 to 2026
$19.5M
NIDDK NIH HHS P30 DK116074
6 · The paper itself

Abstract

This study demonstrates that pulsed focused ultrasound (pFUS) therapy can non-invasively enhance the function and engraftment of pancreatic islets following transplantation. In vitro, we show that islets treated with pFUS at low (peak negative pressure (PNP): 106kPa, spatial peak temporal peak intensity (I

Indexed as

Graft SurvivalAnimalsBlood GlucoseDiabetes Mellitus, ExperimentalInsulin SecretionIslets of LangerhansIslets of Langerhans TransplantationMaleMiceMice, Inbred C57BLUltrasonographyBlood Glucose

Identifiers

PMID31527773
PMCPMC6746980
OpenAlexW2972358340

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.